Synthesis, Characterization and Antioxidant Property of Quercetin-Tb(III) Complex
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Purpose: Nearly all of flavonoids are good metal chelators and can chelate many metal ions to form different complexes. This article describes a synthesis of Quercetin-Tb(III) in methanol, characterized by using elemental analysis, UV-visible and evaluation of its antioxidant properties.
Methods: The formation of complexes is realized from the UV-visible spectra which shows that the successive formation of Quercetin-Tb(III) occurs. To find out the antioxidant activity variation and the role of Tb(III) ion on the antioxidant activity of the complexes different radical scavenging methods such as: 1,1-diphenyl-2-picrylhydrazyl (DPPH), ferric reducing antioxidant power (FRAP) and 2,2'-azinobis 3-ethylbenzothiazoline-6-sulphonic acid (ABTS) were used.
Results: The results from DPPH, ABTS and FRAP methods showed that Quercetin and Quercetin-Tb(III) complex are capable of donating electron or hydrogen atom, and consequently could react with free radicals or terminate chain reactions in a time- and dose-dependent manner.
Conclusion: This study showed that the chelation of metal ions by Quercetin decrease the redox potential of Quercetin-metal complex.
Maliyam P, Laphookhieo S, Koedrith P, Puttarak P Heliyon. 2024; 10(14):e34480.
PMID: 39130464 PMC: 11315074. DOI: 10.1016/j.heliyon.2024.e34480.
Mudi A, Ray S, Bera M, Dolai M, Das M, Kundu P Heliyon. 2023; 9(12):e22712.
PMID: 38125469 PMC: 10731082. DOI: 10.1016/j.heliyon.2023.e22712.
Carvalho D, Pinho C, Oliveira R, Moreira F, Oliveira A Molecules. 2023; 28(23).
PMID: 38067447 PMC: 10708206. DOI: 10.3390/molecules28237714.
Prestianni L, Espinal E, Hathcock S, Vollmuth N, Wang P, Holler R Pharmaceutics. 2023; 15(4).
PMID: 37111527 PMC: 10144594. DOI: 10.3390/pharmaceutics15041041.
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Scibior A Antioxidants (Basel). 2022; 11(4).
PMID: 35453475 PMC: 9029821. DOI: 10.3390/antiox11040790.