Aortic Dilatation in Children with Systemic Hypertension

Overview

Journal J Am Soc Hypertens

Publisher Elsevier

Specialty Cardiology & Vascular Diseases

Date 2014 Feb 11

PMID 24507486

Citations 7

Authors

Monesha Gupta-Malhotra

Richard B Devereux

Archana Dave

Cynthia Bell

Ronald Portman

Diana Milewicz

Affiliations

Soon will be listed here.

Abstract

The aim of the study was to determine the presence of aortic dilatation in hypertensive children, the prevalence of which is 4% to 10% in hypertensive adults. Prospectively enrolled multiethnic children, untreated for their hypertension, underwent an echocardiogram to exclude congenital heart disease and evaluate for end-organ damage and aortic size. The aorta was measured in the parasternal long-axis view at three levels: the sinus of Valsalva, supra-tubular junction, and the ascending aorta. Aortic dilatation was determined by z-score >2 at any one of the levels measured. Hypertension was defined as blood pressure above the 95th percentile based on the Fourth Working Group criteria confirmed by 24-hour ambulatory blood pressure monitoring. Among 142 consecutive hypertensive children (median age, 14 years; 45% females) aortic dilatation was detected in 2.8% (95% confidence interval, 1%-7%; median age, 16 years; 100% females). Children with aortic dilatation, when compared with those without, had significantly more aortic valve insufficiency (P = .005) and left ventricular hypertrophy (P = .018). Prevalence of aortic dilatation was 2.8% and was associated with significantly more aortic insufficiency and left ventricular hypertrophy in comparison to those without aortic dilatation.

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Epidemiology of Childhood Onset Essential Hypertension.

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Left Ventricular Hypertrophy Phenotype in Childhood-Onset Essential Hypertension.

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