Dietary Exposures and Allergy Prevention in High-risk Infants: A Joint Statement with the Canadian Society of Allergy and Clinical Immunology

Overview

Journal Paediatr Child Health

Publisher Oxford University Press

Specialty Pediatrics

Date 2014 Feb 6

PMID 24497783

Citations 21

Authors

Edmond S Chan

Carl Cummings

Affiliations

Soon will be listed here.

Abstract

Allergic conditions in children are a prevalent health concern in Canada. The burden of disease and the societal costs of proper diagnosis and management are considerable, making the primary prevention of allergic conditions a desirable health care objective. This position statement reviews current evidence on dietary exposures and allergy prevention in infants at high risk for developing allergic conditions. It revisits previous dietary recommendations for pregnancy, breastfeeding and formula feeding, and provides an approach for introducing solid foods to high-risk infants. While there is no evidence that delaying the introduction of any specific food beyond six months of age helps to prevent allergy, the protective effect of early introduction of potentially allergenic foods (at four to six months of age) remains under investigation. Recent research appears to suggest that regularly ingesting a new, potentially allergenic food may be as important as when that food is first introduced.

Citing Articles

Prevalence of Clostridium botulinum in Retail Peanut Butters from a 2007 Survey in Ottawa, Canada.

Harris R, Bussey J, Flint A, Blondin-Brosseau M, Weedmark K, Austin J Curr Microbiol. 2024; 81(10):322.

PMID: 39179697 PMC: 11343779. DOI: 10.1007/s00284-024-03843-1.

Prevention of IgE-Mediated Food Allergy: Emerging Strategies Through Maternal and Neonatal Interventions.

Herman K, Brough H, Pier J, Venter C, Jarvinen K J Allergy Clin Immunol Pract. 2024; 12(7):1686-1694.

PMID: 38677585 PMC: 11420814. DOI: 10.1016/j.jaip.2024.04.029.

The Effect of Food Allergen Exclusion on the Growth of Saudi Children.

Bin Obaid M, Abdulaziz AlSedairy S, Alghamdi H, Aljameel G, Alidrissi E, AlZahrani M Children (Basel). 2023; 10(9).

PMID: 37761429 PMC: 10528035. DOI: 10.3390/children10091468.

Dietary exposures and allergy prevention in high-risk infants.

Abrams E, Watson W, Vander Leek T, Atkinson A, Primeau M, Francoeur M Allergy Asthma Clin Immunol. 2022; 18(1):36.

PMID: 35501827 PMC: 9063186. DOI: 10.1186/s13223-021-00638-y.

A systematic review of infant feeding food allergy prevention guidelines - can we AGREE?.

Vale S, Lobb M, Netting M, Murray K, Clifford R, Campbell D World Allergy Organ J. 2021; 14(6):100550.

PMID: 34141050 PMC: 8173304. DOI: 10.1016/j.waojou.2021.100550.

References

Fox A, Sasieni P, Du Toit G, Syed H, Lack G . Household peanut consumption as a risk factor for the development of peanut allergy. J Allergy Clin Immunol. 2009; 123(2):417-23. DOI: 10.1016/j.jaci.2008.12.014. View

Koplin J, Osborne N, Wake M, Martin P, Gurrin L, Robinson M . Can early introduction of egg prevent egg allergy in infants? A population-based study. J Allergy Clin Immunol. 2010; 126(4):807-13. DOI: 10.1016/j.jaci.2010.07.028. View

Nwaru B, Takkinen H, Niemela O, Kaila M, Erkkola M, Ahonen S . Timing of infant feeding in relation to childhood asthma and allergic diseases. J Allergy Clin Immunol. 2012; 131(1):78-86. DOI: 10.1016/j.jaci.2012.10.028. View

Chung C, Yamini S, Trumbo P . FDA's health claim review: whey-protein partially hydrolyzed infant formula and atopic dermatitis. Pediatrics. 2012; 130(2):e408-14. DOI: 10.1542/peds.2012-0333. View

Prescott S, Smith P, Tang M, Palmer D, Sinn J, Huntley S . The importance of early complementary feeding in the development of oral tolerance: concerns and controversies. Pediatr Allergy Immunol. 2008; 19(5):375-80. DOI: 10.1111/j.1399-3038.2008.00718.x. View

Osborne N, Koplin J, Martin P, Gurrin L, Lowe A, Matheson M . Prevalence of challenge-proven IgE-mediated food allergy using population-based sampling and predetermined challenge criteria in infants. J Allergy Clin Immunol. 2011; 127(3):668-76.e1-2. DOI: 10.1016/j.jaci.2011.01.039. View

Muraro A, Dreborg S, Halken S, Host A, Niggemann B, Aalberse R . Dietary prevention of allergic diseases in infants and small children. Part II. Evaluation of methods in allergy prevention studies and sensitization markers. Definitions and diagnostic criteria of allergic diseases. Pediatr Allergy Immunol. 2004; 15(3):196-205. DOI: 10.1111/j.1399-3038.2004.00128.x. View

. New grades for recommendations from the Canadian Task Force on Preventive Health Care. CMAJ. 2003; 169(3):207-8. PMC: 167122. View

Kull I, Bergstrom A, Lilja G, Pershagen G, Wickman M . Fish consumption during the first year of life and development of allergic diseases during childhood. Allergy. 2006; 61(8):1009-15. DOI: 10.1111/j.1398-9995.2006.01115.x. View

10.

Brown S, Asai Y, Cordell H, Campbell L, Zhao Y, Liao H . Loss-of-function variants in the filaggrin gene are a significant risk factor for peanut allergy. J Allergy Clin Immunol. 2011; 127(3):661-7. PMC: 3081065. DOI: 10.1016/j.jaci.2011.01.031. View

11.

Sicherer S, Wood R, Stablein D, Lindblad R, Burks A, Liu A . Maternal consumption of peanut during pregnancy is associated with peanut sensitization in atopic infants. J Allergy Clin Immunol. 2010; 126(6):1191-7. PMC: 3018157. DOI: 10.1016/j.jaci.2010.08.036. View

12.

Kull I, Almqvist C, Lilja G, Pershagen G, Wickman M . Breast-feeding reduces the risk of asthma during the first 4 years of life. J Allergy Clin Immunol. 2004; 114(4):755-60. DOI: 10.1016/j.jaci.2004.07.036. View

13.

Kramer M, Kakuma R . Maternal dietary antigen avoidance during pregnancy or lactation, or both, for preventing or treating atopic disease in the child. Cochrane Database Syst Rev. 2012; (9):CD000133. PMC: 7045459. DOI: 10.1002/14651858.CD000133.pub3. View

14.

Katz Y, Rajuan N, Goldberg M, Eisenberg E, Heyman E, Cohen A . Early exposure to cow's milk protein is protective against IgE-mediated cow's milk protein allergy. J Allergy Clin Immunol. 2010; 126(1):77-82.e1. DOI: 10.1016/j.jaci.2010.04.020. View

15.

Hourihane J, Aiken R, Briggs R, Gudgeon L, Grimshaw K, DunnGalvin A . The impact of government advice to pregnant mothers regarding peanut avoidance on the prevalence of peanut allergy in United Kingdom children at school entry. J Allergy Clin Immunol. 2007; 119(5):1197-202. DOI: 10.1016/j.jaci.2006.12.670. View

16.

Host A, Halken S, Muraro A, Dreborg S, Niggemann B, Aalberse R . Dietary prevention of allergic diseases in infants and small children. Pediatr Allergy Immunol. 2008; 19(1):1-4. DOI: 10.1111/j.1399-3038.2007.00680.x. View

17.

Osborn D, Sinn J . Formulas containing hydrolysed protein for prevention of allergy and food intolerance in infants. Cochrane Database Syst Rev. 2006; (4):CD003664. DOI: 10.1002/14651858.CD003664.pub3. View

18.

Du Toit G, Roberts G, Sayre P, Plaut M, Bahnson H, Mitchell H . Identifying infants at high risk of peanut allergy: the Learning Early About Peanut Allergy (LEAP) screening study. J Allergy Clin Immunol. 2012; 131(1):135-43.e1-12. DOI: 10.1016/j.jaci.2012.09.015. View

19.

Soller L, Ben-Shoshan M, Harrington D, Fragapane J, Joseph L, St Pierre Y . Overall prevalence of self-reported food allergy in Canada. J Allergy Clin Immunol. 2012; 130(4):986-8. DOI: 10.1016/j.jaci.2012.06.029. View

20.

Agostoni C, Decsi T, Fewtrell M, Goulet O, Kolacek S, Koletzko B . Complementary feeding: a commentary by the ESPGHAN Committee on Nutrition. J Pediatr Gastroenterol Nutr. 2007; 46(1):99-110. DOI: 10.1097/01.mpg.0000304464.60788.bd. View