Efficacy and Safety of Sildenafil for the Treatment of Severe Pulmonary Hypertension in Patients with Hemoglobinopathies: Results from a Long-term Follow Up

Overview

Journal Haematologica

Specialty Hematology

Date 2014 Feb 6

PMID 24497563

Citations 4

Authors

Giorgio Derchi

Manuela Balocco

Patrizio Bina

Vincenzo Caruso

Domenico G DAscola

Roberto Littera

Raffaella Origa

Maria D Cappellini

Gian L Forni

Affiliations

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Citing Articles

Cardiac complications in thalassemia throughout the lifespan: Victories and challenges.

Wood J Ann N Y Acad Sci. 2023; 1530(1):64-73.

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Pulmonary hypertension in thalassemia: a call to action.

Wood J Blood. 2022; 139(13):1937-1938.

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Sickle cell disease: a review for the internist.

Pinto V, Balocco M, Quintino S, Forni G Intern Emerg Med. 2019; 14(7):1051-1064.

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Response to "efficacy and safety of sildenafil for the treatment of severe pulmonary hypertension in patients with hemoglobinopathies: results from a long-term follow up " Haematologica 2014;99(2):e17-18.

Klings E, Vichinsky E, Morris C Haematologica. 2014; 99(2):e19.

PMID: 24497564 PMC: 3912978. DOI: 10.3324/haematol.2013.099861.

References

Derchi G, Forni G, Formisano F, Cappellini M, Galanello R, DAscola G . Efficacy and safety of sildenafil in the treatment of severe pulmonary hypertension in patients with hemoglobinopathies. Haematologica. 2005; 90(4):452-8. View

Morris C, Kim H, Wood J, Porter J, Klings E, Trachtenberg F . Sildenafil therapy in thalassemia patients with Doppler-defined risk of pulmonary hypertension. Haematologica. 2013; 98(9):1359-67. PMC: 3762091. DOI: 10.3324/haematol.2012.082065. View

Sebkhi A, Strange J, Phillips S, Wharton J, Wilkins M . Phosphodiesterase type 5 as a target for the treatment of hypoxia-induced pulmonary hypertension. Circulation. 2003; 107(25):3230-5. DOI: 10.1161/01.CIR.0000074226.20466.B1. View

Farmakis D, Aessopos A . Pulmonary hypertension associated with hemoglobinopathies: prevalent but overlooked. Circulation. 2011; 123(11):1227-32. DOI: 10.1161/CIRCULATIONAHA.110.988089. View

Derchi G, Galanello R, Bina P, Cappellini M, Piga A, Lai M . Prevalence and risk factors for pulmonary arterial hypertension in a large group of β-thalassemia patients using right heart catheterization: a Webthal study. Circulation. 2013; 129(3):338-45. DOI: 10.1161/CIRCULATIONAHA.113.002124. View