» Articles » PMID: 24493936

New Bioactive Compounds from Korean Native Mushrooms

Overview
Journal Mycobiology
Date 2014 Feb 5
PMID 24493936
Citations 3
Authors
Affiliations
Soon will be listed here.
Abstract

Mushrooms are ubiquitous in nature and have high nutritional attributes. They have demonstrated diverse biological effects and therefore have been used in treatments of various diseases, including cancer, diabetes, bacterial and viral infections, and ulcer. In particular, polysaccharides, including β-glucan, are considered as the major constituents responsible for the biological activity of mushrooms. Although an overwhelming number of reports have been published on the importance of polysaccharides as immunomodulating agents, not all of the healing properties found in these mushrooms could be fully accounted for. Recently, many research groups have begun investigations on biologically active small-molecular weight compounds in wild mushrooms. In this mini-review, both structural diversity and biological activities of novel bioactive substances from Korean native mushrooms are described.

Citing Articles

Wild mushrooms showed analgesic and cytotoxic properties along with phytoconstituent's binding affinity to COX-1, COX-2 and cytochrome P450 2C9.

Hossen S, Hossain M, Akbar S, Tahmida U, Mawa J, Emon N Heliyon. 2021; 7(9):e07997.

PMID: 34585013 PMC: 8455681. DOI: 10.1016/j.heliyon.2021.e07997.


Neuraminidase Inhibitors from the Fruiting Body of Phellinus igniarius.

Kim J, Kim D, Hwang B, Woo E, Lee Y, Jeong K Mycobiology. 2016; 44(2):117-20.

PMID: 27433123 PMC: 4945539. DOI: 10.5941/MYCO.2016.44.2.117.


Lipoxygenase Inhibitory Activity of Korean Indigenous Mushroom Extracts and Isolation of an Active Compound from Phellinus baumii.

Lee S, Song J, Hwang B, Kim D, Lee Y, Woo E Mycobiology. 2014; 42(2):185-8.

PMID: 25071389 PMC: 4112236. DOI: 10.5941/MYCO.2014.42.2.185.

References
1.
Lee I, Yun B . Highly oxygenated and unsaturated metabolites providing a diversity of hispidin class antioxidants in the medicinal mushrooms Inonotus and Phellinus. Bioorg Med Chem. 2007; 15(10):3309-14. DOI: 10.1016/j.bmc.2007.03.039. View

2.
Yun B, Kang H, Koshino H, Yu S, Yoo I . Suillusin, a unique benzofuran from the mushroom Suillus granulatus. J Nat Prod. 2001; 64(9):1230-1. DOI: 10.1021/np010138a. View

3.
Yamasaki A, Shoda M, Iijima H, Nagai S, Wada J, Suzuki H . A protein-bound polysaccharide, PSK, enhances tumor suppression induced by docetaxel in a gastric cancer xenograft model. Anticancer Res. 2009; 29(3):843-50. View

4.
Jang Y, Lee I, Kim Y, Lee S, Lee H, Yu S . Xylarinic acids A and B, new antifungal polypropionates from the fruiting body of Xylaria polymorpha. J Antibiot (Tokyo). 2007; 60(11):696-9. DOI: 10.1038/ja.2007.89. View

5.
Yun B, Lee I, Kim J, Yoo I . Leucomentin-5 and -6, two new leucomentin derivatives from the mushroom Paxillus panuoides. J Antibiot (Tokyo). 2000; 53(7):711-3. DOI: 10.7164/antibiotics.53.711. View