Microfluidic Cell Culture

Overview

Journal Curr Opin Biotechnol

Publisher Elsevier

Specialty Biotechnology

Date 2014 Feb 4

PMID 24484886

Citations 121

Authors

Matthias Mehling

Savas Tay

Affiliations

Soon will be listed here.

Abstract

Microfluidic techniques allow precise control of fluids and particles at the nanoliter scale and facilitate simultaneous manipulation and analysis of cultured cells, starting from a single cell to larger populations and to intact tissues. The use of integrated microfluidic devices has considerably advanced the fields of quantitative and systems biology. In this review, we survey the recent developments in microfluidic cell culture, and discuss not only the advantages but also limitations of using such systems, and give an outlook on potential future developments.

Citing Articles

Rapid Fluid Velocity Field Prediction in Microfluidic Mixers via Nine Grid Network Model.

Li Q, Chen Y, Sun T, Wang J Micromachines (Basel). 2025; 16(1).

PMID: 39858660 PMC: 11767880. DOI: 10.3390/mi16010005.

On-chip non-contact mechanical cell stimulation - quantification of SKOV-3 alignment to suspended microstructures.

Onal S, Alkaisi M, Nock V Heliyon. 2025; 11(1):e41433.

PMID: 39844975 PMC: 11751512. DOI: 10.1016/j.heliyon.2024.e41433.

Gastrointestinal Cancer Patient Derived Organoids at the Frontier of Personalized Medicine and Drug Screening.

Yang Z, Yu J, Wong C Cells. 2024; 13(16.

PMID: 39195202 PMC: 11352269. DOI: 10.3390/cells13161312.

Advances in Microfluidic Systems and Numerical Modeling in Biomedical Applications: A Review.

Ferreira M, Carvalho V, Ribeiro J, Lima R, Teixeira S, Pinho D Micromachines (Basel). 2024; 15(7).

PMID: 39064385 PMC: 11279158. DOI: 10.3390/mi15070873.

Harnessing the potential of hydrogels for advanced therapeutic applications: current achievements and future directions.

Lu P, Ruan D, Huang M, Tian M, Zhu K, Gan Z Signal Transduct Target Ther. 2024; 9(1):166.

PMID: 38945949 PMC: 11214942. DOI: 10.1038/s41392-024-01852-x.