The Effects of Two Lactobacillus Plantarum Strains on Rat Lipid Metabolism Receiving a High Fat Diet

Overview

Journal ScientificWorldJournal

Publisher Wiley

Specialty Biology

Date 2014 Jan 29

PMID 24470789

Citations 30

Authors

Rastislav Salaj

Jana Stofilova

Alena Soltesova

Zdenka Hertelyova

Emilia Hijova

Izabela Bertkova

Ladislav Strojny

Peter Kruzliak

Alojz Bomba

Affiliations

Soon will be listed here.

Abstract

The aim of our study was to evaluate the effects of the different probiotic strains, Lactobacillus plantarum LS/07 and Lactobacillus plantarum Biocenol LP96, on lipid metabolism and body weight in rats fed a high fat diet. Compared with the high fat diet group, the results showed that Lactobacillus plantarum LS/07 reduced serum cholesterol and LDL cholesterol, but Lactobacillus plantarum Biocenol LP96 decreased triglycerides and VLDL, while there was no change in the serum HDL level and liver lipids. Both probiotic strains lowered total bile acids in serum. Our strains have no significant change in body weight, gain weight, and body fat. These findings indicate that the effect of lactobacilli on lipid metabolism may differ among strains and that the Lactobacillus plantarum LS/07 and Lactobacillus plantarum Biocenol LP96 can be used to improve lipid profile and can contribute to a healthier bowel microbial balance.

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