Changes in Bladder Wall Thickness and Detrusor Wall Thickness After Surgical Treatment of Benign Prostatic Enlargement in Patients with Lower Urinary Tract Symptoms: a Preliminary Report

Overview

Journal Korean J Urol

Specialty Urology

Date 2014 Jan 28

PMID 24466397

Citations 7

Authors

Hakmin Lee

Minsoo Choo

Myong Kim

Sung Yong Cho

Seung Bae Lee

Hyeon Jeong

Hwancheoul Son

Affiliations

Soon will be listed here.

Abstract

Purpose: The purpose of the present study was to evaluate the perioperative changes in bladder wall thickness and detrusor wall thickness after transurethral prostatectomy.

Materials And Methods: Fifty-one men who were treated for benign prostatic hyperplasia/lower urinary tract symptoms with transurethral prostatectomy were prospectively analyzed from May 2012 to July 2013. Prostate size, detrusor wall thickness, and bladder wall thickness were assessed by transrectal and transabdominal ultrasonography perioperatively. All postoperative evaluations were performed 1 month after the surgery.

Results: The patients' mean age was 69.0 years, the mean prostate-specific antigen concentration was 8.1 ng/mL, and the mean prostate volume was 63.2 mL. The mean bladder wall thickness was 5.1 mm (standard deviation [SD], ±1.6), 5.1 mm (SD, ±1.6), and 5.0 mm (SD, ±1.4) preoperatively and 4.5 mm (SD, ±1.5), 4.5 mm (SD, ±1.3), and 4.6 mm (SD, ±1.2) postoperatively in the anterior wall, dome, and trigone, respectively (p=0.178, p=0.086, and p=0.339, respectively). The mean detrusor wall thickness was 0.9 mm (SD, ±0.4) preoperatively and 0.7 mm (SD, ±0.3) postoperatively (p=0.001). A subgroup analysis stratifying patients into a large prostate group (weight, ≥45 g) and a high Abrams-Griffiths number group (>30) showed a significant decrease in detrusor wall thickness (p=0.002, p=0.018).

Conclusions: There was a decrease in detrusor wall thickness after transurethral prostatectomy. The large prostate group and the high Abrams-Griffiths number group showed a significant decrease in detrusor wall thickness after surgery.

Citing Articles

Deep Learning and Numerical Analysis for Bladder Outflow Obstruction and Detrusor Underactivity Diagnosis in Men: A Novel Urodynamic Evaluation Scheme.

Mei H, Wang Z, Zheng Q, Jiao P, Lv S, Liu X Neurourol Urodyn. 2025; 44(2):512-519.

PMID: 39803869 PMC: 11788940. DOI: 10.1002/nau.25665.

Recent developments in diagnostic ultrasound for lower urinary tract function.

Minagawa T J Med Ultrason (2001). 2024; .

PMID: 39327335 DOI: 10.1007/s10396-024-01494-0.

Efficiency of HoLEP in patients with detrusor underactivity and renal dysfunction secondary to BPO.

Yang D, Sun Q, Li W, Wang Y, Qian H, Li D World J Urol. 2024; 42(1):509.

PMID: 39240342 PMC: 11379783. DOI: 10.1007/s00345-024-05208-6.

De-obstruction of bladder outlet in humans reverses organ remodelling by normalizing the expression of key transcription factors.

Akshay A, Gheinani A, Besic M, Braga S, Uldry A, Heller M BMC Urol. 2024; 24(1):33.

PMID: 38326801 PMC: 10848355. DOI: 10.1186/s12894-024-01417-8.

[Diagnostic work-up of benign prostatic hyperplasia : The German S2e-guideline 2023 part 1].

Oelke M, Abt S, Becher K, Dreikorn K, Madersbacher S, Magistro G Urologie. 2023; 62(8):805-817.

PMID: 37401972 DOI: 10.1007/s00120-023-02142-0.

References

Chalana V, Dudycha S, Yuk J, McMorrow G . Automatic Measurement of Ultrasound-Estimated Bladder Weight (UEBW) from Three-Dimensional Ultrasound. Rev Urol. 2006; 7 Suppl 6:S22-8. PMC: 1557412. View

Mirone V, Imbimbo C, Longo N, Fusco F . The detrusor muscle: an innocent victim of bladder outlet obstruction. Eur Urol. 2006; 51(1):57-66. DOI: 10.1016/j.eururo.2006.07.050. View

Isikay L, Akgul K, Nuhoglu B, Ozdemir G, Ayyildiz A, Cavumirza T . Lower urinary tract symptoms, prostate volume, uroflowmetry, residual urine volume and bladder wall thickness in Turkish men: a comparative analysis. Int Urol Nephrol. 2007; 39(4):1131-5. DOI: 10.1007/s11255-006-9161-y. View

Housami F, Drake M, Abrams P . The use of ultrasound-estimated bladder weight in diagnosing bladder outlet obstruction and detrusor overactivity in men with lower urinary tract symptoms. Indian J Urol. 2009; 25(1):105-9. PMC: 2684305. DOI: 10.4103/0970-1591.45547. View

Klingler H, Madersbacher S, Djavan B, Schatzl G, Marberger M, Schmidbauer C . Morbidity of the evaluation of the lower urinary tract with transurethral multichannel pressure-flow studies. J Urol. 1997; 159(1):191-4. DOI: 10.1016/s0022-5347(01)64054-0. View

Oelke M, Hofner K, Jonas U, de la Rosette J, Ubbink D, Wijkstra H . Diagnostic accuracy of noninvasive tests to evaluate bladder outlet obstruction in men: detrusor wall thickness, uroflowmetry, postvoid residual urine, and prostate volume. Eur Urol. 2007; 52(3):827-34. DOI: 10.1016/j.eururo.2006.12.023. View

Nitti V . Pressure flow urodynamic studies: the gold standard for diagnosing bladder outlet obstruction. Rev Urol. 2006; 7 Suppl 6:S14-21. PMC: 1477621. View

Levin R, HAUGAARD N, OConnor L, Buttyan R, Das A, Dixon J . Obstructive response of human bladder to BPH vs. rabbit bladder response to partial outlet obstruction: a direct comparison. Neurourol Urodyn. 2000; 19(5):609-29. DOI: 10.1002/1520-6777(2000)19:5<609::aid-nau7>3.0.co;2-h. View

Nielsen K, Andersen C, Petersen L, Oxlund H, Nordling J . Morphological, stereological, and biochemical analysis of the mini-pig urinary bladder after chronic outflow obstruction and after recovery from obstruction. Neurourol Urodyn. 1995; 14(3):269-84. DOI: 10.1002/nau.1930140308. View

10.

Bright E, Oelke M, Tubaro A, Abrams P . Ultrasound estimated bladder weight and measurement of bladder wall thickness--useful noninvasive methods for assessing the lower urinary tract?. J Urol. 2010; 184(5):1847-54. DOI: 10.1016/j.juro.2010.06.006. View

11.

Kojima M, Inui E, Ochiai A, Naya Y, Ukimura O, Watanabe H . Ultrasonic estimation of bladder weight as a measure of bladder hypertrophy in men with infravesical obstruction: a preliminary report. Urology. 1996; 47(6):942-7. DOI: 10.1016/S0090-4295(96)00059-3. View

12.

Manieri C, Carter S, Romano G, Trucchi A, Valenti M, Tubaro A . The diagnosis of bladder outlet obstruction in men by ultrasound measurement of bladder wall thickness. J Urol. 1998; 159(3):761-5. View

13.

Ochiai A, Kojima M . Correlation of ultrasound-estimated bladder weight with ultrasound appearance of the prostate and postvoid residual urine in men with lower urinary tract symptoms. Urology. 1998; 51(5):722-9. DOI: 10.1016/s0090-4295(98)00020-x. View

14.

Kojima M, Inui E, Ochiai A, Naya Y, Kamoi K, Ukimura O . Reversible change of bladder hypertrophy due to benign prostatic hyperplasia after surgical relief of obstruction. J Urol. 1997; 158(1):89-93. DOI: 10.1097/00005392-199707000-00024. View

15.

Kessler T, Gerber R, Burkhard F, Studer U, Danuser H . Ultrasound assessment of detrusor thickness in men-can it predict bladder outlet obstruction and replace pressure flow study?. J Urol. 2006; 175(6):2170-3. DOI: 10.1016/S0022-5347(06)00316-8. View

16.

Oelke M, Hofner K, Jonas U, Ubbink D, de la Rosette J, Wijkstra H . Ultrasound measurement of detrusor wall thickness in healthy adults. Neurourol Urodyn. 2006; 25(4):308-17. DOI: 10.1002/nau.20242. View

17.

Oelke M, Hofner K, Wiese B, Grunewald V, Jonas U . Increase in detrusor wall thickness indicates bladder outlet obstruction (BOO) in men. World J Urol. 2002; 19(6):443-52. DOI: 10.1007/s00345-001-0238-z. View