A Large Parosteal Ossifying Lipoma of Lower Limb Encircling the Femur

Overview

Journal Int Arch Med

Publisher iMedPub

Specialty General Medicine

Date 2014 Jan 18

PMID 24433545

Citations 4

Authors

Atif Ali Hashmi

Babar Malik

Muhammad Muzzammil Edhi

Naveen Faridi

Muhammad Ashraful

Affiliations

Soon will be listed here.

Abstract

Introduction: Lipoma is a benign soft tissue neoplasm that may contain mesenchymal elements, as a result of metaplastic process. Ossification in benign and malignant soft tissue tumors can also manifest due to metaplastic process.

Case Presentation: A 45 year old woman presented with a large thigh mass. The mass was developed one and a half year ago which insidiously increased in size and was associated with movement restriction. Radiological findings revealed soft tissue neoplasm on antero-medial aspect of thigh encircling the femur and displacing adjacent muscles. Fine trabeculations were seen in neoplasm suggestive of ossification. Excision of the mass was performed and histopathology revealed adipocytes with mature bony trabeculae possessing prominent osteoblastic rimming suggestive of ossifying lipoma.

Conclusion: It is important to recognize this variant of lipoma as it is associated with a better clinical outcome in contrast to most of the deep seated soft tissue neoplasms. Secondly it should also be differentiated from myositis ossificans and heterologous differentiation in other soft tissue neoplasms. We suggest an algorithmic approach to the diagnosis of ossifying soft tissue neoplasms histopathologically. Mature bony trabeculae with prominent osteoblastic rimming in a soft tissue lesion are due to a metaplastic process and should not be confused with osteosarcoma.

Citing Articles

Parosteal lipoma of the forearm: A case report and a literature review.

Al-Mnayyis A, Al Sharie S, Araydah M, Talafha M, Haddad F Medicine (Baltimore). 2021; 100(46):e27876.

PMID: 34797330 PMC: 8601361. DOI: 10.1097/MD.0000000000027876.

Parosteal ossifying lipoma of the clavicle: A case report.

Nie P, Guo J, Xu Y, He Z, Han M, Dai B Mol Clin Oncol. 2017; 6(3):419-421.

PMID: 28451424 PMC: 5403469. DOI: 10.3892/mco.2017.1135.

Osteolipoma of the knee.

Huynh T, Cipriano C, Hagemann I, Friedman M Radiol Case Rep. 2017; 12(1):124-129.

PMID: 28228894 PMC: 5310264. DOI: 10.1016/j.radcr.2016.10.015.

Ossifying parosteal lipoma of the thoracic spine: a case report and review of literature.

Myint Z, Chow R, Wang L, Chou P J Community Hosp Intern Med Perspect. 2015; 5(1):26013.

PMID: 25656666 PMC: 4318815. DOI: 10.3402/jchimp.v5.26013.

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