Successful Use of Locally Applied Polyhexamethylene Biguanide As an Adjunct to the Treatment of Fungal Osteomyelitis

Overview

Journal Can J Infect Dis Med Microbiol

Publisher Wiley

Date 2014 Jan 15

PMID 24421812

Citations 6

Authors

Genevieve Walls

Lisa Noonan

Elizabeth Wilson

David Holland

Simon Briggs

Affiliations

Soon will be listed here.

Abstract

Fungal osteomyelitis is rare in immunocompetent patients and is often difficult to cure, even with optimal medical and surgical management. The authors present two cases of fungal osteomyelitis in which the common swimming pool cleaner, polyhexamethylene biguanide, was used successfully as an adjunct to standard surgical and medical treatment. Also presented is a literature review on the use of polyhexamethylene biguanide for this indication. The authors recommend that this safe and well-tolerated compound be considered as part of the treatment for fungal osteomyelitis.

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