Post-study Caffeine Administration Enhances Memory Consolidation in Humans

Overview

Journal Nat Neurosci

Date 2014 Jan 14

PMID 24413697

Citations 77

Authors

Daniel Borota

Elizabeth Murray

Gizem Keceli

Allen Chang

Joseph M Watabe

Maria Ly

John P Toscano

Michael A Yassa

Affiliations

Soon will be listed here.

Abstract

It is currently not known whether caffeine has an enhancing effect on long-term memory in humans. We used post-study caffeine administration to test its effect on memory consolidation using a behavioral discrimination task. Caffeine enhanced performance 24 h after administration according to an inverted U-shaped dose-response curve; this effect was specific to consolidation and not retrieval. We conclude that caffeine enhanced consolidation of long-term memories in humans.

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