Cleft Lip - a Comprehensive Review

Overview

Journal Front Pediatr

Specialty Pediatrics

Date 2014 Jan 9

PMID 24400297

Citations 53

Authors

Mahdi A Shkoukani

Michael Chen

Angela Vong

Affiliations

Soon will be listed here.

Abstract

Orofacial clefts comprise a range of congenital deformities and are the most common head and neck congenital malformation. Clefting has significant psychological and socio- economic effects on patient quality of life and require a multidisciplinary team approach for management. The complex interplay between genetic and environmental factors play a significant role in the incidence and cause of clefting. In this review, the embryology, classification, epidemiology, and etiology of cleft lip are discussed. The primary goals of surgical repair are to restore normal function, speech development, and facial esthetics. Different techniques are employed based on surgeon expertise and the unique patient presentations. Pre-surgical orthopedics are frequently employed prior to definitive repair to improve outcomes. Long term follow up and quality of life studies are discussed.

Citing Articles

Differences in Tooth Development in Patients With Unilateral Cleft Lip and Palate.

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Global, regional, and national survey on burden and Quality of Care Index (QCI) of orofacial clefts: Global burden of disease systematic analysis 1990-2019.

Sofi-Mahmudi A, Shamsoddin E, Khademioore S, Khazaei Y, Vahdati A, Tovani-Palone M PLoS One. 2025; 20(1):e0317267.

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Low-Dose Cone-Beam Computed Tomography in Swedish Pediatric Patients With Alveolar Clefts Following Alveolar Bone Grafting-A Clinical Study.

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Comparative Evaluation of Temporomandibular Joint Parameters in Unilateral and Bilateral Cleft Lip and Palate Patients Using Cone-Beam CT: Focus on Growing vs. Non-Growing Subjects.

Abdelkarim A, Almeshari A, Celik Ozen D, Khalifa A, Rezallah N, Duman S Healthcare (Basel). 2024; 12(16).

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