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Silicone Oil with High Specific Gravity for Intraocular Use

Overview
Journal Br J Ophthalmol
Specialty Ophthalmology
Date 1987 Apr 1
PMID 2437955
Citations 20
Authors
V P Gabel
A Kampik
C Gabel
D Spiegel
Affiliations
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Abstract

Silicone oil with a higher specific gravity than that of intraocular fluid or polydimethylsiloxane may have special indications in vitreoretinal surgery. Trifluorsiloxane is such a substance, and therefore its biological compatibility was investigated in rabbit eyes. It was found that this substance was clinically well tolerated within the observation time of up to 6 months, even if there was some neovascularisation from the inferior limbus. Histologically both an inflammatory response and tissue impregnation were more pronounced than with normal polydimethylsiloxane.

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References
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