Cytochemical Localization of Ca++-ATPase Activity in the Lateral Cochlear Wall of the Guinea Pig

Overview

Journal Arch Otorhinolaryngol

Specialty Otorhinolaryngology

Date 1987 Jan 1

PMID 2436605

Citations 7

Authors

T Yoshihara

M Igarashi

Affiliations

Soon will be listed here.

Abstract

Ca++-ATPase activity was examined cytochemically in the lateral cochlear wall of the guinea pig. The reaction products showing Ca++-ATPase activity were found along the folded plasma membrane of the strial marginal cells. In contrast, little or no reaction was seen on the apical surfaces of these cells. There were also marked reaction products on the microvilli and the endolymphatic cell surface of Reissner's membrane, and the apical and lateral plasma membranes of the spiral prominence and the external sulcus cells. These reactions completely disappeared when Ca++ or ATP was removed from the incubation medium. Our results strongly suggest that Ca++-ATPase plays an important role in Ca++ transport system for the regulation of Ca++ concentration in the cochlear endolymph.

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