GENSAT BAC Cre-recombinase Driver Lines to Study the Functional Organization of Cerebral Cortical and Basal Ganglia Circuits

Overview

Journal Neuron

Publisher Cell Press

Specialty Neurology

Date 2013 Dec 24

PMID 24360541

Citations 372

Authors

Charles R Gerfen

Ronald Paletzki

Nathaniel Heintz

Affiliations

Soon will be listed here.

Abstract

Recent development of molecular genetic techniques are rapidly advancing understanding of the functional role of brain circuits in behavior. Critical to this approach is the ability to target specific neuron populations and circuits. The collection of over 250 BAC Cre-recombinase driver lines produced by the GENSAT project provides a resource for such studies. Here we provide characterization of GENSAT BAC-Cre driver lines with expression in specific neuroanatomical pathways within the cerebral cortex and basal ganglia.

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