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Live Human Nasal Epithelial Cells (hNECs) on Chip for in Vitro Testing of Gaseous Formaldehyde Toxicity Via Airway Delivery

Overview
Journal Lab Chip
Specialties Biotechnology
Chemistry
Date 2013 Dec 21
PMID 24356185
Citations 15
Authors
Affiliations
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Abstract

Cell models based on human nasal epithelial stem/progenitor cells (hNESPCs) are developed to obtain functional ciliated cells on modified Transwell inserts. The live hNECs are integrated into microfluidic platforms to mimic the 3D features of the human upper airway for in vitro testing of gaseous formaldehyde toxicity via airway delivery.

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