The Influence of Fat Infiltration of Back Extensor Muscles on Osteoporotic Vertebral Fractures

Overview

Journal Asian Spine J

Date 2013 Dec 20

PMID 24353848

Citations 5

Authors

Kwang-Young So

Dae-Hee Kim

Dong-Hyuk Choi

Choong-Young Kim

Jeong-Seok Kim

Yong-Soo Choi

Affiliations

Soon will be listed here.

Abstract

Study Design: Retrospective study.

Purpose: To investigate the influence of fat infiltration at low back extensor muscles on osteoporotic vertebral fracture.

Overview Of Literature: In persons with stronger back muscles, the risk of osteoporotic vertebral fractures will likely be lower than in those persons with weaker back muscles. However, the degree of influence of fat infiltration of the back extensor muscle on osteoporotic vertebral fracture remains controversial.

Methods: Two hundred and thirty-seven patients who had undergone lumbar spine magnetic resonance imaging and bone mineral density (BMD) were enrolled in this study. The amount of low back extensor muscle was determined using the pseudocoloring technique on an axial view of the L3 level. The patients were divided into two groups: osteoporotic vertebral fracture group (group A) and non-fracture group (group B). The amount of low back extensor muscle is compared with BMD, degenerative change of disc, osteophyte grade of facet joint and promontory angle to reveal the association between these factors.

Results: A negative correlation is found between age and the amount of low back extensor muscle (p=0.001). The amount of low back extensor muscle in group A and group B was 60.3%±14.5% and 64.2%±9.3% respectively, thus showing a significantly smaller amount of low back extensor muscle in the osteoporotic vertebral fracture group (p=0.015).

Conclusions: Fat infiltration of low back extensor muscle was increased in osteoporotic vertebral fracture patients. Therefore, fat infiltration of low back extensor muscle in an elderly person may be a risk factor of osteoporotic vertebral fracture.

Citing Articles

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References

Pruitt L, Taaffe D, Marcus R . Effects of a one-year high-intensity versus low-intensity resistance training program on bone mineral density in older women. J Bone Miner Res. 1995; 10(11):1788-95. DOI: 10.1002/jbmr.5650101123. View

Briggs A, Greig A, Wark J, Fazzalari N, Bennell K . A review of anatomical and mechanical factors affecting vertebral body integrity. Int J Med Sci. 2005; 1(3):170-180. PMC: 1074712. DOI: 10.7150/ijms.1.170. View

Halle J, Smidt G, ODwyer K, Lin S . Relationship between trunk muscle torque and bone mineral content of the lumbar spine and hip in healthy postmenopausal women. Phys Ther. 1990; 70(11):690-9. DOI: 10.1093/ptj/70.11.690. View

Oleksik A, Lips P, Dawson A, Minshall M, Shen W, Cooper C . Health-related quality of life in postmenopausal women with low BMD with or without prevalent vertebral fractures. J Bone Miner Res. 2000; 15(7):1384-92. DOI: 10.1359/jbmr.2000.15.7.1384. View

Gleeson P, Protas E, Leblanc A, Schneider V, Evans H . Effects of weight lifting on bone mineral density in premenopausal women. J Bone Miner Res. 1990; 5(2):153-8. DOI: 10.1002/jbmr.5650050208. View

Bassey E, Rothwell M, Littlewood J, PYE D . Pre- and postmenopausal women have different bone mineral density responses to the same high-impact exercise. J Bone Miner Res. 1998; 13(12):1805-13. DOI: 10.1359/jbmr.1998.13.12.1805. View

Sinaki M, Wahner H, Offord K, Hodgson S . Efficacy of nonloading exercises in prevention of vertebral bone loss in postmenopausal women: a controlled trial. Mayo Clin Proc. 1989; 64(7):762-9. DOI: 10.1016/s0025-6196(12)61748-0. View

Nachemson A . The load on lumbar disks in different positions of the body. Clin Orthop Relat Res. 1966; 45:107-22. View

Hayes W, Myers E . Biomechanical considerations of hip and spine fractures in osteoporotic bone. Instr Course Lect. 1997; 46:431-8. View

10.

Sinaki M, Wollan P, Scott R, Gelczer R . Can strong back extensors prevent vertebral fractures in women with osteoporosis?. Mayo Clin Proc. 1996; 71(10):951-6. DOI: 10.1016/S0025-6196(11)63768-3. View

11.

Sinaki M, Nwaogwugwu N, Phillips B, Mokri M . Effect of gender, age, and anthropometry on axial and appendicular muscle strength. Am J Phys Med Rehabil. 2001; 80(5):330-8. DOI: 10.1097/00002060-200105000-00002. View

12.

Sinaki M, Itoi E, Wahner H, Wollan P, Gelzcer R, Mullan B . Stronger back muscles reduce the incidence of vertebral fractures: a prospective 10 year follow-up of postmenopausal women. Bone. 2002; 30(6):836-41. DOI: 10.1016/s8756-3282(02)00739-1. View

13.

Sinaki M, McPhee M, Hodgson S, Merritt J, Offord K . Relationship between bone mineral density of spine and strength of back extensors in healthy postmenopausal women. Mayo Clin Proc. 1986; 61(2):116-22. DOI: 10.1016/s0025-6196(12)65197-0. View

14.

Parkkola R, Rytokoski U, Kormano M . Magnetic resonance imaging of the discs and trunk muscles in patients with chronic low back pain and healthy control subjects. Spine (Phila Pa 1976). 1993; 18(7):830-6. DOI: 10.1097/00007632-199306000-00004. View

15.

Kohrt W, Snead D, Slatopolsky E, BIRGE Jr S . Additive effects of weight-bearing exercise and estrogen on bone mineral density in older women. J Bone Miner Res. 1995; 10(9):1303-11. DOI: 10.1002/jbmr.5650100906. View

16.

Felsenberg D, Silman A, Lunt M, Armbrecht G, Ismail A, Finn J . Incidence of vertebral fracture in europe: results from the European Prospective Osteoporosis Study (EPOS). J Bone Miner Res. 2002; 17(4):716-24. DOI: 10.1359/jbmr.2002.17.4.716. View

17.

Pfirrmann C, Metzdorf A, Zanetti M, Hodler J, Boos N . Magnetic resonance classification of lumbar intervertebral disc degeneration. Spine (Phila Pa 1976). 2001; 26(17):1873-8. DOI: 10.1097/00007632-200109010-00011. View

18.

Lee J, Cha J, Kim Y, Kim Y, Shin B . Quantitative analysis of back muscle degeneration in the patients with the degenerative lumbar flat back using a digital image analysis: comparison with the normal controls. Spine (Phila Pa 1976). 2008; 33(3):318-25. DOI: 10.1097/BRS.0b013e318162458f. View

19.

Myers E, Wilson S . Biomechanics of osteoporosis and vertebral fracture. Spine (Phila Pa 1976). 1998; 22(24 Suppl):25S-31S. DOI: 10.1097/00007632-199712151-00005. View

20.

Sievanen H, Kannus P, Nieminen V, Heinonen A, Oja P, Vuori I . Estimation of various mechanical characteristics of human bones using dual energy X-ray absorptiometry: methodology and precision. Bone. 1996; 18(1 Suppl):17S-27S. DOI: 10.1016/8756-3282(95)00376-2. View