» Articles » PMID: 24353724

Outcome of Conventional IVF and ICSI on Sibling Oocytes in Moderate Ligoasthenozoospermia

Overview
Journal Pak J Med Sci
Specialty General Medicine
Date 2013 Dec 20
PMID 24353724
Citations 5
Authors
Affiliations
Soon will be listed here.
Abstract

Objective: To evaluate the outcomes of patients with moderate oligoasthenozoospermia treated with conventional in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI).

Methods: A total of 99 couples with moderate oligoasthenozoospermia undergoing their first IVF/ICSI cycle were included in the study. Sibling oocytes were randomized to be inseminated either by conventional IVF or ICSI. Fertilization rate, cleavage rate, embryo quality, implantation rate, and clinical pregnancy rate were examined.

Results: There was no difference in the fertilization rate, cleavage rate, implantation rate, and pregnancy rate between conventional IVF and ICSI (P>0.05). The good quality embryo rate was significant difference between after IVF and after ICSI (P<0.05).

Conclusions: Couples with moderate oligoasthenozoospermia did not influence the major indices of IVF and the uncertainties concerning the safety of ICSI, couples with moderate oligoasthenozoospermia need not be subjected to ICSI.

Citing Articles

The effect of azoospermia factor microdeletions on intracytoplasmic sperm injection results in azoospermia patients.

Emirdar V, Acet F Pak J Med Sci. 2023; 39(3):672-676.

PMID: 37250564 PMC: 10214791. DOI: 10.12669/pjms.39.3.7003.


What Does Intracytoplasmic Sperm Injection Change in Embryonic Development? The Spermatozoon Contribution.

Chamayou S, Giacone F, Cannarella R, Guglielmino A J Clin Med. 2023; 12(2).

PMID: 36675600 PMC: 9867417. DOI: 10.3390/jcm12020671.


Considerations on staffing levels for a modern assisted reproductive laboratory.

Sciorio R, Aiello R, Janssens R JBRA Assist Reprod. 2022; 27(1):120-130.

PMID: 36515254 PMC: 10065777. DOI: 10.5935/1518-0557.20220048.


More blastocysts are produced from fewer oocytes in ICSI  compared to IVF - results from a sibling oocytes study and definition of a new key performance indicator.

Chamayou S, Ragolia C, Alecci C, Storaci G, Romano S, Sapienza R Reprod Biol Endocrinol. 2021; 19(1):116.

PMID: 34311751 PMC: 8311920. DOI: 10.1186/s12958-021-00804-2.


Intracytoplasmic sperm injection (ICSI) versus conventional in vitro fertilisation (IVF) in couples with non-severe male infertility (NSMI-ICSI): protocol for a multicentre randomised controlled trial.

Zheng D, Zeng L, Yang R, Lian Y, Zhu Y, Liang X BMJ Open. 2019; 9(9):e030366.

PMID: 31575574 PMC: 6773417. DOI: 10.1136/bmjopen-2019-030366.

References
1.
Schnorr J, Brown S, Oehninger S, Mayer J, Muasher S, Lanzendorf S . Impact of intracytoplasmic sperm injection on embryo cryopreservation and clinical outcome. Fertil Steril. 2001; 75(3):636-7. DOI: 10.1016/s0015-0282(00)01734-9. View

2.
Griffiths T, Murdoch A, Herbert M . Embryonic development in vitro is compromised by the ICSI procedure. Hum Reprod. 2000; 15(7):1592-6. DOI: 10.1093/humrep/15.7.1592. View

3.
Sarkar N . Intracytoplasmic sperm injection: an assisted reproductive technique and its outcome to overcome infertility. J Obstet Gynaecol. 2007; 27(4):347-53. DOI: 10.1080/01443610701327339. View

4.
Khamsi F, Yavas Y, Roberge S, Wong J, Lacanna I, Endman M . Intracytoplasmic sperm injection increased fertilization and good-quality embryo formation in patients with non-male factor indications for in vitro fertilization: a prospective randomized study. Fertil Steril. 2001; 75(2):342-7. DOI: 10.1016/s0015-0282(00)01674-5. View

5.
Macas E, Imthurn B, Borsos M, Rosselli M, Keller P . Impairment of the developmental potential of frozen-thawed human zygotes obtained after intracytoplasmic sperm injection. Fertil Steril. 1998; 69(4):630-5. DOI: 10.1016/s0015-0282(98)00021-1. View