Interlaboratory Comparison of Size Measurements on Nanoparticles Using Nanoparticle Tracking Analysis (NTA)

Overview

Journal J Nanopart Res

Specialty Biomedical Engineering

Date 2013 Dec 19

PMID 24348090

Citations 65

Authors

Patrick Hole

Katherine Sillence

Claire Hannell

Ciaran Manus Maguire

Matthias Roesslein

Guillaume Suarez

Sonja Capracotta

Zuzana Magdolenova

Limor Horev-Azaria

Agnieszka Dybowska

Laura Cooke

Andrea Haase

Servane Contal

Stein Mano

Antje Vennemann

Jeans-Jacques Sauvain

Kieran Crosbie Staunton

Sergio Anguissola

Andreas Luch

Maria Dusinska

Rafi Korenstein

Arno C Gutleb

Martin Wiemann

Adriele Prina-Mello

Michael Riediker

Peter Wick

Affiliations

Soon will be listed here.

Abstract

One of the key challenges in the field of nanoparticle (NP) analysis is in producing reliable and reproducible characterisation data for nanomaterials. This study looks at the reproducibility using a relatively new, but rapidly adopted, technique, Nanoparticle Tracking Analysis (NTA) on a range of particle sizes and materials in several different media. It describes the protocol development and presents both the data and analysis of results obtained from 12 laboratories, mostly based in Europe, who are primarily QualityNano members. QualityNano is an EU FP7 funded Research Infrastructure that integrates 28 European analytical and experimental facilities in nanotechnology, medicine and natural sciences with the goal of developing and implementing best practice and quality in all aspects of nanosafety assessment. This study looks at both the development of the protocol and how this leads to highly reproducible results amongst participants. In this study, the parameter being measured is the modal particle size.

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