Patten-Elliott F, Lei C, Preston S, Wilkinson R, Mirams G
Philos Trans A Math Phys Eng Sci. 2025; 383(2292):20240227.
PMID: 40078143
PMC: 11904620.
DOI: 10.1098/rsta.2024.0227.
Chaudhary K, Clancy C, Yang P, Pierson J, Goldin A, Koerner J
Clin Transl Sci. 2024; 17(12):e70098.
PMID: 39660576
PMC: 11632537.
DOI: 10.1111/cts.70098.
Gray R, Franz M
Am J Physiol Heart Circ Physiol. 2023; 325(5):H952-H964.
PMID: 37656133
PMC: 10907032.
DOI: 10.1152/ajpheart.00227.2023.
Uzelac I, Kaboudian A, Iravanian S, Siles-Paredes J, Gumbart J, Ashikaga H
Heart Rhythm O2. 2021; 2(4):394-404.
PMID: 34430945
PMC: 8369304.
DOI: 10.1016/j.hroo.2021.06.008.
Hesketh L, Wilder C, Ranadive N, Lytra G, Qazimi P, Munro J
Sci Rep. 2020; 10(1):8397.
PMID: 32439959
PMC: 7242333.
DOI: 10.1038/s41598-020-65190-y.
Pharmacological Profile of the Sodium Current in Human Stem Cell-Derived Cardiomyocytes Compares to Heterologous Nav1.5+β1 Model.
Van de Sande D, Kopljar I, Teisman A, Gallacher D, Snyders D, Lu H
Front Pharmacol. 2020; 10:1374.
PMID: 31920633
PMC: 6917651.
DOI: 10.3389/fphar.2019.01374.
Computational Modeling of Electrophysiology and Pharmacotherapy of Atrial Fibrillation: Recent Advances and Future Challenges.
Vagos M, van Herck I, Sundnes J, Arevalo H, Edwards A, Koivumaki J
Front Physiol. 2018; 9:1221.
PMID: 30233399
PMC: 6131668.
DOI: 10.3389/fphys.2018.01221.
Time-dependent antiarrhythmic effects of flecainide on induced atrial fibrillation in horses.
Carstensen H, Hesselkilde E, Fenner M, Loft-Andersen A, Flethoj M, Kanters J
J Vet Intern Med. 2018; 32(5):1708-1717.
PMID: 30133839
PMC: 6189357.
DOI: 10.1111/jvim.15287.
Pharmacological and toxicological activity of RSD921, a novel sodium channel blocker.
Walker M, Hayes E, Saint D, Adaikan G, Abraham S, Goldin A
Biomed Pharmacother. 2018; 106:510-522.
PMID: 29990839
PMC: 6492542.
DOI: 10.1016/j.biopha.2018.06.157.
Predicting QRS and PR interval prolongations in humans using nonclinical data.
Bergenholm L, Parkinson J, Mettetal J, Evans N, Chappell M, Collins T
Br J Pharmacol. 2017; 174(19):3268-3283.
PMID: 28675424
PMC: 5595766.
DOI: 10.1111/bph.13940.
Role of Sodium Channels in Epilepsy.
Kaplan D, Isom L, Petrou S
Cold Spring Harb Perspect Med. 2016; 6(6).
PMID: 27143702
PMC: 4888813.
DOI: 10.1101/cshperspect.a022814.
Actions of flecainide on susceptibility to phase-2 ventricular arrhythmias during infarct evolution in rat isolated perfused hearts.
Clements-Jewery H, Kanaganayagam G, Kabra R, Curtis M
Br J Pharmacol. 2006; 147(5):468-75.
PMID: 16415912
PMC: 1616984.
DOI: 10.1038/sj.bjp.0706633.
Antiarrhythmic drug research.
Walker M
Br J Pharmacol. 2006; 147 Suppl 1:S222-31.
PMID: 16402108
PMC: 1760742.
DOI: 10.1038/sj.bjp.0706500.
Effects of hyperkalaemia on the depression of maximum rate of depolarization by class I antiarrhythmic agents in guinea-pig myocardium.
Wyse K, Ye V, Campbell T
Br J Pharmacol. 1993; 108(1):255-61.
PMID: 8428209
PMC: 1907716.
DOI: 10.1111/j.1476-5381.1993.tb13471.x.
Reversal of lidocaine effects on sodium currents by isoproterenol in rabbit hearts and heart cells.
Lee H, Matsuda J, Reynertson S, Martins J, Shibata E
J Clin Invest. 1993; 91(2):693-701.
PMID: 8381826
PMC: 288011.
DOI: 10.1172/JCI116250.
Drug effects on the electrocardiogram. A review of their clinical importance.
Symanski J, GETTES L
Drugs. 1993; 46(2):219-48.
PMID: 7691513
DOI: 10.2165/00003495-199346020-00002.
Electrocardiographic interactions between pinacidil, a potassium channel opener and class I antiarrhythmic agents in guinea-pig isolated perfused heart.
Yang Q, Padrini R, Bova S, Piovan D, Magnolfi G
Br J Pharmacol. 1995; 114(8):1745-9.
PMID: 7599944
PMC: 1510383.
DOI: 10.1111/j.1476-5381.1995.tb14966.x.
Block of single cardiac Na+ channels by antiarrhythmic drugs: the effect of amiodarone, propafenone and diprafenone.
KOHLHARDT M, Fichtner H
J Membr Biol. 1988; 102(2):105-19.
PMID: 2458471
DOI: 10.1007/BF01870449.
Use-dependent effects of pirmenol on Vmax and conduction in guinea-pig ventricular myocardium.
Hasegawa J, Hirai S, Noguchi N, Hisatome I, Kotake H, Mashiba H
Br J Pharmacol. 1990; 99(4):815-9.
PMID: 2361175
PMC: 1917544.
DOI: 10.1111/j.1476-5381.1990.tb13012.x.
Electrophysiological effects of the combination of mexiletine and flecainide in guinea-pig ventricular fibres.
Delpon E, Valenzuela C, Tamargo J
Br J Pharmacol. 1991; 103(2):1411-6.
PMID: 1909200
PMC: 1908390.
DOI: 10.1111/j.1476-5381.1991.tb09803.x.
