Electrocorticographic Correlates of Overt Articulation of 44 English Phonemes: Intracranial Recording in Children with Focal Epilepsy

Overview

Journal Clin Neurophysiol

Publisher Elsevier

Specialties Neurology
Psychiatry

Date 2013 Dec 10

PMID 24315545

Citations 11

Authors

Goichiro Toyoda

Erik C Brown

Naoyuki Matsuzaki

Katsuaki Kojima

Masaaki Nishida

Eishi Asano

Affiliations

Soon will be listed here.

Abstract

Objective: We determined the temporal-spatial patterns of electrocorticography (ECoG) signal modulation during overt articulation of 44 American English phonemes.

Methods: We studied two children with focal epilepsy who underwent extraoperative ECoG recording. Using animation movies, we delineated 'when' and 'where' gamma- (70-110 Hz) and low-frequency-band activities (10-30 Hz) were modulated during self-paced articulation.

Results: Regardless of the classes of phoneme articulated, gamma-augmentation initially involved a common site within the left inferior Rolandic area. Subsequently, gamma-augmentation and/or attenuation involved distinct sites within the left oral-sensorimotor area with a timing variable across phonemes. Finally, gamma-augmentation in a larynx-sensorimotor area took place uniformly at the onset of sound generation, and effectively distinguished voiced and voiceless phonemes. Gamma-attenuation involved the left inferior-frontal and superior-temporal regions simultaneously during articulation. Low-frequency band attenuation involved widespread regions including the frontal, temporal, and parietal regions.

Conclusions: Our preliminary results support the notion that articulation of distinct phonemes recruits specific sensorimotor activation and deactivation. Gamma attenuation in the left inferior-frontal and superior-temporal regions may reflect transient functional suppression in these cortical regions during automatic, self-paced vocalization of phonemes containing no semantic or syntactic information.

Significance: Further studies are warranted to determine if measurement of event-related modulations of gamma-band activity, compared to that of the low-frequency-band, is more useful for decoding the underlying articulatory functions.

Citing Articles

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Mapping Human Laryngeal Motor Cortex during Vocalization.

Eichert N, Papp D, Mars R, Watkins K Cereb Cortex. 2020; 30(12):6254-6269.

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Nishida M, Korzeniewska A, Crone N, Toyoda G, Nakai Y, Ofen N Clin Neurophysiol. 2017; 128(8):1473-1487.

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