Autophagy-mediated Tumor Promotion

Overview

Journal Cell

Publisher Cell Press

Specialty Cell Biology

Date 2013 Dec 10

PMID 24315093

Citations 277

Authors

Jessie Yanxiang Guo

Bing Xia

Eileen White

Affiliations

Soon will be listed here.

Abstract

Mouse models for cancer are revealing novel cancer-promoting roles for autophagy. Autophagy promotes tumor growth by suppressing the p53 response, maintaining mitochondrial function, sustaining metabolic homeostasis and survival in stress, and preventing diversion of tumor progression to benign oncocytomas.

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