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Detection of Single Nanoparticles and Lentiviruses Using Microcavity Resonance Broadening

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Journal Adv Mater
Date 2013 Dec 5
PMID 24303524
Citations 45
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Abstract

A new label-free sensing mechanism is demonstrated experimentally by monitoring the whispering-gallery mode broadening in microcavities. It is immune to both noise from the probe laser and environmental disturbances, and is able to remove the strict requirement for ultra-high-Q mode cavities for sensitive nanoparticle detection. This ability to sense nanoscale objects and biological analytes is particularly crucial for wide applications.

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