Pyruvate Kinase Binding to Particles in Brain

Overview

Journal Neurochem Res

Specialties Chemistry
Neurology

Date 2013 Nov 26

PMID 24272238

Citations 2

Authors

H R Knull

Affiliations

Soon will be listed here.

Abstract

Interaction of pyruvate kinase with membrane fractions of rat brain homogenates was shown to be electrostatic. Ionic compounds readily solubilized the enzyme from membranes, and the enzyme was more readily solubilized at high pH versus low pH. Developmental patterns indicated that the particulate and soluble forms of pyruvate kinase increased nearly in synchrony from birth until maturity.

Citing Articles

Glycogen metabolizing enzymes in brain.

Knull H, Khandelwal R Neurochem Res. 1982; 7(10):1307-17.

PMID: 6218421 DOI: 10.1007/BF00965901.

Immunohistochemical localization of pyruvate kinase isoenzymes in chicken tissues.

Reinacher M, Eigenbrodt E, Schering B, Schoner W Histochemistry. 1979; 64(2):145-61.

PMID: 393663 DOI: 10.1007/BF00490095.

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