» Articles » PMID: 24271568

Translocation of Neural Modulators a Second Category of Nerve Signal

Overview
Journal Neurochem Res
Specialties Chemistry
Neurology
Date 2013 Nov 26
PMID 24271568
Citations 1
Authors
Affiliations
Soon will be listed here.
Abstract

Translocation of substances that modulate cell-firing in the brain occurs in neural systems. Some of these substances are considered to be intermediary in the actions of neurotransmitters, and they or their metabolites undergo translocation both intracellularly and extracellularly, in and among established neural structures. The movements, in suitable circumstances, are now proposed to have the status of signal-transmission complementary to that of the orthodox nerve impulse, but traveling at 10(-6)-10(-7) times its speed.

Citing Articles

Adenine mononucleotides and their metabolites liberated from and applied to isolated tissues of the mammalian brain.

Pull I, McIlwain H Neurochem Res. 2013; 2(2):203-16.

PMID: 24271953 DOI: 10.1007/BF00964097.

References
1.
Shimizu H, Creveling C, Daly J . Stimulated formation of adenosine 3',5'-cyclic phosphate in cerebral cortex: synergism between electrical activity and biogenic amines. Proc Natl Acad Sci U S A. 1970; 65(4):1033-40. PMC: 283019. DOI: 10.1073/pnas.65.4.1033. View

2.
Lindl T, Cramer H . Compartmentation of an ATP substrate pool for histamine and adrenaline sensitive adenylate cyclase in rat superior cervical ganglia. Biochem Pharmacol. 1975; 24(9):947-50. DOI: 10.1016/0006-2952(75)90424-4. View

3.
Browning E, Schwartz J, BRECKENRIDGE B . Norepinephrine-sensitive properties of C-6 astrocytoma cells. Mol Pharmacol. 1974; 10(1):162-74. View

4.
MASCHERPA P . [Psychostimulating effect of adenosine in the mouse]. Arzneimittelforschung. 1971; 2:25-6. View

5.
Jungmann R, Lee S, DeAngelo A . Translocation of cytoplasmic protein kinase and cyclic adenosine monophosphate-binding protein to intracellular acceptor sites. Adv Cyclic Nucleotide Res. 1975; 5:281-306. View