A FORTRAN Program for the Calculation and Analysis of Two-locus Linkage Disequilibrium Coefficients

Overview

Journal Theor Appl Genet

Publisher Springer

Specialty Genetics

Date 2013 Nov 21

PMID 24253058

Citations 27

Authors

W C Black 4th

E S Krafsur

Affiliations

Soon will be listed here.

Abstract

A FORTRAN program was written that calculates composite linkage disequilibrium coefficients from genotypic data. Chi-square tests determine whether coefficients calculated for allele and locus pairs are significantly greater than zero. A subroutine is provided that partitions the variance in linkage disequilibrium into within- and between-subpopulation components. Output obtained from analysis of allozyme data collected from natural subpopulations of the house fly (Musca domestica L.) are included to illustrate features of the program.

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