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High Pressure Trapping in Fourier Transform Mass Spectrometry: A Radiofrequency-only-mode Event

Overview
Journal J Am Soc Mass Spectrom
Specialty Chemistry
Date 2013 Nov 16
PMID 24234503
Citations 7
Authors
D L Rempel
M L Gross
Affiliations
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Abstract

A new event for the Fourier transform mass spectrometry (FTMS) sequence is developed and demonstrated. During this event, called a radiofrequency (RF)-only mode event, the typical passive cubic trap of a Fourier transform mass spectrometer is made to operate as an active quadrupole ion trap. The transition between active and passive modes is developed so that ion loss as a consequence of the transition can be held to 15% or less. The adduct of the ion-molecule reaction of the 1,3-butadiene radical cation and methyl vinyl ether was detected during the Rf-only-mode event at a helium pressure of ∼1×10(-3) torr even though this adduct is not detectable under standard FTMS operating conditions.

Citing Articles

A PERSPECTIVE ON PERSONAL CONTRIBUTIONS TO FT-ICR MASS SPECTROMETRY.

Gross M, Rempel D Mass Spectrom Rev. 2020; 41(2):178-193.

PMID: 32960989 PMC: 8888036. DOI: 10.1002/mas.21657.

Ion cloud manipulation using the radiofrequency-only-mode as an improvement for high mass detection in fourier transform mass spectrometry.

Jacoby C, Holliman C, Rempel D, Gross M J Am Soc Mass Spectrom. 2013; 4(2):186-9.

PMID: 24234799 DOI: 10.1016/1044-0305(93)85076-A.

Characterization of an electron ionization source trap operating in the presence of a magnetic field through computer simulation.

Vitcher S, Charvy C, Dudragne L, Tabet J J Am Soc Mass Spectrom. 2013; 24(7):1130-6.

PMID: 23715869 DOI: 10.1007/s13361-013-0641-x.

Atmospheric pressure MALDI-FTMS of normal and chemically modified RNA.

Kellersberger K, Yu E, Merenbloom S, Fabris D J Am Soc Mass Spectrom. 2005; 16(2):199-207.

PMID: 15694770 DOI: 10.1016/j.jasms.2004.10.008.

Evaluation of different combinations of gated trapping, RF-only mode and trap compensation for in-field MALDI Fourier transform mass spectrometry.

Gooden J, Rempel D, Gross M J Am Soc Mass Spectrom. 2004; 15(7):1109-15.

PMID: 15234369 DOI: 10.1016/j.jasms.2004.05.006.

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