» Articles » PMID: 24206838

Middle East Respiratory Syndrome Coronavirus in Bats, Saudi Arabia

Abstract

The source of human infection with Middle East respiratory syndrome coronavirus remains unknown. Molecular investigation indicated that bats in Saudi Arabia are infected with several alphacoronaviruses and betacoronaviruses. Virus from 1 bat showed 100% nucleotide identity to virus from the human index case-patient. Bats might play a role in human infection.

Citing Articles

Evolutionary Relationships of Unclassified Coronaviruses in Canadian Bat Species.

Simon A, Badmalia M, Paquette S, Manalaysay J, Czekay D, Kandel B Viruses. 2025; 16(12.

PMID: 39772188 PMC: 11680298. DOI: 10.3390/v16121878.


Improving the reporting of metagenomic virome-scale data.

Chang W, Harvey E, Mahar J, Firth C, Shi M, Simon-Loriere E Commun Biol. 2024; 7(1):1687.

PMID: 39706917 PMC: 11662069. DOI: 10.1038/s42003-024-07212-3.


A panoramic view of the molecular epidemiology, evolution, and cross-species transmission of rosaviruses.

Zhang M, Fan S, Liang M, Wu R, Tian J, Xian J Vet Res. 2024; 55(1):145.

PMID: 39516900 PMC: 11545274. DOI: 10.1186/s13567-024-01399-3.


An Analysis of Combined Molecular Weight and Hydrophobicity Similarity between the Amino Acid Sequences of Spike Protein Receptor Binding Domains of Betacoronaviruses and Functionally Similar Sequences from Other Virus Families.

Dixson J, Vumma L, Azad R Microorganisms. 2024; 12(10).

PMID: 39458330 PMC: 11510113. DOI: 10.3390/microorganisms12102021.


Disease tolerance as immune defense strategy in bats: One size fits all?.

Pei G, Balkema-Buschmann A, Dorhoi A PLoS Pathog. 2024; 20(9):e1012471.

PMID: 39236038 PMC: 11376593. DOI: 10.1371/journal.ppat.1012471.


References
1.
Teeling E, Springer M, Madsen O, Bates P, OBrien S, Murphy W . A molecular phylogeny for bats illuminates biogeography and the fossil record. Science. 2005; 307(5709):580-4. DOI: 10.1126/science.1105113. View

2.
Watanabe S, Masangkay J, Nagata N, Morikawa S, Mizutani T, Fukushi S . Bat coronaviruses and experimental infection of bats, the Philippines. Emerg Infect Dis. 2010; 16(8):1217-23. PMC: 3298303. DOI: 10.3201/eid1608.100208. View

3.
Zaki A, van Boheemen S, Bestebroer T, Osterhaus A, Fouchier R . Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia. N Engl J Med. 2012; 367(19):1814-20. DOI: 10.1056/NEJMoa1211721. View

4.
Corman V, Eckerle I, Bleicker T, Zaki A, Landt O, Eschbach-Bludau M . Detection of a novel human coronavirus by real-time reverse-transcription polymerase chain reaction. Euro Surveill. 2012; 17(39). DOI: 10.2807/ese.17.39.20285-en. View

5.
Ithete N, Stoffberg S, Corman V, Cottontail V, Richards L, Schoeman M . Close relative of human Middle East respiratory syndrome coronavirus in bat, South Africa. Emerg Infect Dis. 2013; 19(10):1697-9. PMC: 3810765. DOI: 10.3201/eid1910.130946. View