Long-lasting Insecticidal Nets Are Synergistic with Mass Drug Administration for Interruption of Lymphatic Filariasis Transmission in Nigeria

Overview

Journal PLoS Negl Trop Dis

Specialties Infectious Diseases
Tropical Medicine

Date 2013 Nov 9

PMID 24205421

Citations 22

Authors

Abel Eigege

Alphonsus Kal

Emmanuel Miri

Adamu Sallau

John Umaru

Hayward Mafuyai

Yohanna S Chuwang

Goshit Danjuma

Jacob Danboyi

Solomon E Adelamo

Bulus S Mancha

Bridget Okoeguale

Amy E Patterson

Lindsay Rakers

Frank O Richards

Affiliations

Soon will be listed here.

Abstract

In central Nigeria Anopheles mosquitoes transmit malaria and lymphatic filariasis (LF). The strategy used for interrupting LF transmission in this area is annual mass drug administration (MDA) with albendazole and ivermectin, but after 8 years of MDA, entomological evaluations in sentinel villages showed continued low-grade mosquito infection rates of 0.32%. After long-lasting insecticidal net (LLIN) distribution by the national malaria program in late 2010, however, we were no longer able to detect infected vectors over a 24-month period. This is evidence that LLINs are synergistic with MDA in interrupting LF transmission.

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Smith M, Griswold E, Singh B, Miri E, Eigege A, Adelamo S PLoS Comput Biol. 2020; 16(7):e1007506.

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