The Disposable Soma Theory of Aging in Reverse
Overview
Authors
Affiliations
In a recent paper in Nature, Ermolaeva et al. uncover a systemic response to DNA damage in germ cells that protects somatic tissues, providing mechanistic insight into the bidirectional communication between germ line and soma.
Nunn A, Guy G, Bell J Int J Mol Sci. 2023; 24(17).
PMID: 37685877 PMC: 10488084. DOI: 10.3390/ijms241713070.
Kyriazis M, Swas L, Orlova T J Clin Med. 2023; 12(16).
PMID: 37629475 PMC: 10455615. DOI: 10.3390/jcm12165433.
The soma-germline communication: implications for somatic and reproductive aging.
Gaddy M, Kuang S, Alfhili M, Lee M BMB Rep. 2021; 54(5):253-259.
PMID: 33407997 PMC: 8167245.
Essential role of autophagy in resource allocation during sexual reproduction.
Gao H, Khawar M, Li W Autophagy. 2019; 16(1):18-27.
PMID: 31203720 PMC: 6984600. DOI: 10.1080/15548627.2019.1628543.
Ageing Throughout History: The Evolution of Human Lifespan.
Kyriazis M J Mol Evol. 2019; 88(1):57-65.
PMID: 31197416 DOI: 10.1007/s00239-019-09896-2.