Application of Bioinformatics in Chronobiology Research
Overview
Authors
Affiliations
Bioinformatics and other well-established sciences, such as molecular biology, genetics, and biochemistry, provide a scientific approach for the analysis of data generated through "omics" projects that may be used in studies of chronobiology. The results of studies that apply these techniques demonstrate how they significantly aided the understanding of chronobiology. However, bioinformatics tools alone cannot eliminate the need for an understanding of the field of research or the data to be considered, nor can such tools replace analysts and researchers. It is often necessary to conduct an evaluation of the results of a data mining effort to determine the degree of reliability. To this end, familiarity with the field of investigation is necessary. It is evident that the knowledge that has been accumulated through chronobiology and the use of tools derived from bioinformatics has contributed to the recognition and understanding of the patterns and biological rhythms found in living organisms. The current work aims to develop new and important applications in the near future through chronobiology research.
Disruption in daily eating-fasting and activity-rest cycles in Indian adolescents attending school.
Gupta N, Khare A PLoS One. 2020; 15(1):e0227002.
PMID: 31923256 PMC: 6953840. DOI: 10.1371/journal.pone.0227002.
Systems Biology Approaches and Precision Oral Health: A Circadian Clock Perspective.
Adeola H, Papagerakis S, Papagerakis P Front Physiol. 2019; 10:399.
PMID: 31040792 PMC: 6476986. DOI: 10.3389/fphys.2019.00399.