Real-time Segmentation and Tracking of Brain Metabolic State in ICU EEG Recordings of Burst Suppression
Overview
Affiliations
We provide a method for estimating brain metabolic state based on a reduced-order model of EEG burst suppression. The model, derived from previously suggested biophysical mechanisms of burst suppression, describes important electrophysiological features and provides a direct link to cerebral metabolic rate. We design and fit the estimation method from EEG recordings of burst suppression from a neurological intensive care unit and test it on real and synthetic data.
Individualized survival predictions using state space model with longitudinal and survival data.
Cauchi M, Mills A, Lawrie A, Kiely D, Kadirkamanathan V J R Soc Interface. 2024; 21(216):20230682.
PMID: 39081111 PMC: 11289657. DOI: 10.1098/rsif.2023.0682.
Shivdat S, Zhan T, De Palma A, Zheng W, Krishnamurthy P, Paneerselvam E Neurocrit Care. 2024; 42(1):175-184.
PMID: 39043984 PMC: 11757804. DOI: 10.1007/s12028-024-02047-6.
Towards a potent and rapidly reversible Dexmedetomidine-based general anesthetic.
Xie Z, Fong R, Fox A PLoS One. 2023; 18(9):e0291827.
PMID: 37751454 PMC: 10522005. DOI: 10.1371/journal.pone.0291827.
Reese M, Christensen S, Anolick H, Roberts K, Wong M, Wright M Front Aging Neurosci. 2023; 15:1229081.
PMID: 37711992 PMC: 10499509. DOI: 10.3389/fnagi.2023.1229081.
Ren S, Zang C, Yuan F, Yan X, Zhang Y, Yuan S Aging Clin Exp Res. 2023; 35(9):1873-1879.
PMID: 37479909 DOI: 10.1007/s40520-023-02460-5.