Distress, Problems and Supportive Care Needs of Patients Treated with Auto- or Allo-SCT

Overview

Journal Bone Marrow Transplant

Specialty General Surgery

Date 2013 Oct 8

PMID 24096825

Citations 18

Authors

A M J Braamse

B van Meijel

O Visser

P C Huijgens

A T F Beekman

J Dekker

Affiliations

Soon will be listed here.

Abstract

Hematological malignancies and treatment with hematopoietic SCT are known to affect patients' quality of life. The problem profile and care needs of this patient group need clarification, however. This study aimed to assess distress, problems and care needs after allo- or auto-SCT, and to identify risk factors for distress, problems or care needs. In this cross-sectional study, patients treated with allo-SCT or auto-SCT for hematological malignancies completed the Distress Thermometer and Problem List. Three patient groups were created: 0-1, 1-2.5 and 2.5-5.5 years after transplantation. After allo-SCT, distress and the number of problems tended to be lower with longer follow-up. After auto-SCT, distress was highest at 1-2.5 year(s). Patients mainly reported physical problems, followed by cognitive-emotional and practical problems. A minority reported care needs. Risk factors for distress as well as problems after allo-SCT included younger age, shorter time after transplantation and GVHD. A risk factor for distress as well as problems after auto-SCT was the presence of comorbid diseases. Up to 5 years after auto-SCT or allo-SCT, patients continue to experience distress and problems. Judged by prevalence, physical problems are first priority in supportive care, followed by cognitive-emotional and practical problems.

Citing Articles

Healthcare Professionals' Ratings and Views of Person-Centred Care in the Context of Allogeneic Hematopoietic Stem Cell Transplantation.

OSullivan A, Winterling J, Malmborg Kisch A, Bergkvist K, Edvardsson D, Wengstrom Y Health Serv Insights. 2025; 18:11786329241310735.

PMID: 39760071 PMC: 11694289. DOI: 10.1177/11786329241310735.

Patients' Experiences of Person-Centered Care in the Context of Allogenic Stem Cell Transplantation.

OSullivan A, Hagelin C, Holmberg K, Bergkvist K, Bala S, Wengstrom Y Clin Nurs Res. 2024; 34(2):86-94.

PMID: 39663900 PMC: 11789425. DOI: 10.1177/10547738241302393.

Common patient-reported sources of cancer-related distress in adults with cancer: A systematic review.

Stevens J, Montgomery K, Miller M, Saeidzadeh S, Kwekkeboom K Cancer Med. 2024; 13(13):e7450.

PMID: 38989923 PMC: 11238242. DOI: 10.1002/cam4.7450.

Toward an improved conceptualization of emotions in patients with cancer.

Dekker J, Doppenberg-Smit E, Braamse A, Lamers F, van Linde M, Verheul H Front Psychiatry. 2024; 15:1352026.

PMID: 38600981 PMC: 11004313. DOI: 10.3389/fpsyt.2024.1352026.

Update on Prevalence of Pain in Patients with Cancer 2022: A Systematic Literature Review and Meta-Analysis.

Snijders R, Brom L, Theunissen M, van den Beuken-van Everdingen M Cancers (Basel). 2023; 15(3).

PMID: 36765547 PMC: 9913127. DOI: 10.3390/cancers15030591.

References

Li J, Girgis A . Supportive care needs: are patients with lung cancer a neglected population?. Psychooncology. 2005; 15(6):509-16. DOI: 10.1002/pon.983. View

Roth A, Kornblith A, Batel-Copel L, Peabody E, Scher H, Holland J . Rapid screening for psychologic distress in men with prostate carcinoma: a pilot study. Cancer. 1998; 82(10):1904-8. DOI: 10.1002/(sici)1097-0142(19980515)82:10<1904::aid-cncr13>3.0.co;2-x. View

Lichtman M . Battling the hematological malignancies: the 200 years' war. Oncologist. 2008; 13(2):126-38. DOI: 10.1634/theoncologist.2007-0228. View

Tuinman M, Gazendam-Donofrio S, Hoekstra-Weebers J . Screening and referral for psychosocial distress in oncologic practice: use of the Distress Thermometer. Cancer. 2008; 113(4):870-8. DOI: 10.1002/cncr.23622. View

Jacobsen P, Donovan K, Trask P, Fleishman S, Zabora J, Baker F . Screening for psychologic distress in ambulatory cancer patients. Cancer. 2005; 103(7):1494-502. DOI: 10.1002/cncr.20940. View

Thygesen K, Schjodt I, Jarden M . The impact of hematopoietic stem cell transplantation on sexuality: a systematic review of the literature. Bone Marrow Transplant. 2011; 47(5):716-24. DOI: 10.1038/bmt.2011.169. View

Ferguson R, Ahles T, Saykin A, McDonald B, Furstenberg C, Cole B . Cognitive-behavioral management of chemotherapy-related cognitive change. Psychooncology. 2006; 16(8):772-7. PMC: 3482484. DOI: 10.1002/pon.1133. View

Wiskemann J, Huber G . Physical exercise as adjuvant therapy for patients undergoing hematopoietic stem cell transplantation. Bone Marrow Transplant. 2007; 41(4):321-9. DOI: 10.1038/sj.bmt.1705917. View

Mosher C, DuHamel K, Rini C, Corner G, Lam J, Redd W . Quality of life concerns and depression among hematopoietic stem cell transplant survivors. Support Care Cancer. 2010; 19(9):1357-65. PMC: 3760694. DOI: 10.1007/s00520-010-0958-y. View

10.

Manitta V, Zordan R, Cole-Sinclair M, Nandurkar H, Philip J . The symptom burden of patients with hematological malignancy: a cross-sectional observational study. J Pain Symptom Manage. 2011; 42(3):432-42. DOI: 10.1016/j.jpainsymman.2010.12.008. View

11.

Pidala J, Anasetti C, Jim H . Health-related quality of life following haematopoietic cell transplantation: patient education, evaluation and intervention. Br J Haematol. 2009; 148(3):373-85. PMC: 2810350. DOI: 10.1111/j.1365-2141.2009.07992.x. View

12.

Bonanno G, Westphal M, Mancini A . Resilience to loss and potential trauma. Annu Rev Clin Psychol. 2010; 7:511-35. DOI: 10.1146/annurev-clinpsy-032210-104526. View

13.

Pidala J, Anasetti C, Jim H . Quality of life after allogeneic hematopoietic cell transplantation. Blood. 2009; 114(1):7-19. PMC: 2710956. DOI: 10.1182/blood-2008-10-182592. View

14.

Syrjala K, Yi J, Artherholt S, Stover A, Abrams J . Measuring musculoskeletal symptoms in cancer survivors who receive hematopoietic cell transplantation. J Cancer Surviv. 2010; 4(3):225-35. PMC: 3288113. DOI: 10.1007/s11764-010-0126-x. View

15.

Faller H, Schuler M, Richard M, Heckl U, Weis J, Kuffner R . Effects of psycho-oncologic interventions on emotional distress and quality of life in adult patients with cancer: systematic review and meta-analysis. J Clin Oncol. 2013; 31(6):782-93. DOI: 10.1200/JCO.2011.40.8922. View

16.

Yi J, Syrjala K . Sexuality after hematopoietic stem cell transplantation. Cancer J. 2009; 15(1):57-64. PMC: 2691724. DOI: 10.1097/PPO.0b013e318198c758. View

17.

Lobb E, Joske D, Butow P, Kristjanson L, Cannell P, Cull G . When the safety net of treatment has been removed: patients' unmet needs at the completion of treatment for haematological malignancies. Patient Educ Couns. 2009; 77(1):103-8. DOI: 10.1016/j.pec.2009.02.005. View

18.

Filipovich A, Weisdorf D, Pavletic S, Socie G, Wingard J, Lee S . National Institutes of Health consensus development project on criteria for clinical trials in chronic graft-versus-host disease: I. Diagnosis and staging working group report. Biol Blood Marrow Transplant. 2005; 11(12):945-56. DOI: 10.1016/j.bbmt.2005.09.004. View

19.

Harrison J, Young J, Price M, Butow P, Solomon M . What are the unmet supportive care needs of people with cancer? A systematic review. Support Care Cancer. 2009; 17(8):1117-28. DOI: 10.1007/s00520-009-0615-5. View

20.

Syrjala K, Langer S, Abrams J, Storer B, Martin P . Late effects of hematopoietic cell transplantation among 10-year adult survivors compared with case-matched controls. J Clin Oncol. 2005; 23(27):6596-606. DOI: 10.1200/JCO.2005.12.674. View