Boundary Cartilage Lubrication: Review of Current Concepts

Overview

Journal Wien Med Wochenschr

Specialty General Medicine

Date 2013 Oct 2

PMID 24081750

Citations 17

Authors

Matej Daniel

Affiliations

Soon will be listed here.

Abstract

Effective lubrication of synovial joints is important to prevent cartilage degeneration and to keep the joints healthy. This paper sets out the basics of engineering lubrication with respect to the composition and properties of synovial fluid constituents. Two basic types of boundary lubrication are discussed: the presence of highly hydrophilic proteoglycans that provide a water liquid film, and the existence of multilamellar phospholipids lubricating layers at the surface ofarticular cartilage. Based on current knowledge, we may conclude that no single mechanism of boundary lubrication exists, and that effective boundary lubrication of synovial joints is maintained by the synergic effect of all synovial fluid constituents.

Citing Articles

Cartilage Integrity: A Review of Mechanical and Frictional Properties and Repair Approaches in Osteoarthritis.

Krakowski P, Rejniak A, Sobczyk J, Karpinski R Healthcare (Basel). 2024; 12(16).

PMID: 39201206 PMC: 11353818. DOI: 10.3390/healthcare12161648.

O-glycans Expand Lubricin and Attenuate Its Viscosity and Shear Thinning.

Boushehri S, Holey H, Brosz M, Gumbsch P, Pastewka L, Aponte-Santamaria C Biomacromolecules. 2024; 25(7):3893-3908.

PMID: 38815979 PMC: 11238335. DOI: 10.1021/acs.biomac.3c01348.

Brushing Up on Cartilage Lubrication: Polyelectrolyte-Enhanced Tribological Rehydration.

Elkington R, Hall R, Beadling A, Pandit H, Bryant M Langmuir. 2024; 40(20):10648-10662.

PMID: 38712915 PMC: 11112737. DOI: 10.1021/acs.langmuir.4c00598.

Lipid Anchoring Improves Lubrication and Wear Resistance of the Collagen I Matrix.

Yuan H, Cheng H, Mears L, Huang R, Su R, Qi W Langmuir. 2021; 37(47):13810-13815.

PMID: 34788036 PMC: 8638261. DOI: 10.1021/acs.langmuir.1c01581.

Vibroarthrographic analysis of patellofemoral joint arthrokinematics during squats with increasing external loads.

Olowiana E, Selkow N, Laudner K, Puciato D, Baczkowicz D BMC Sports Sci Med Rehabil. 2020; 12:51.

PMID: 32874592 PMC: 7457288. DOI: 10.1186/s13102-020-00201-z.

References

Kumar P, Oka M, Toguchida J, Kobayashi M, Uchida E, Nakamura T . Role of uppermost superficial surface layer of articular cartilage in the lubrication mechanism of joints. J Anat. 2001; 199(Pt 3):241-50. PMC: 1468328. DOI: 10.1046/j.1469-7580.2001.19930241.x. View

Zea-Aragon Z, Terada N, Ohtsuki K, Ohnishi M, Ohno S . Immunohistochemical localization of phosphatidylcholine in rat mandibular condylar surface and lower joint cavity by cryotechniques. Histol Histopathol. 2005; 20(2):531-6. DOI: 10.14670/HH-20.531. View

Radin E, Swann D, Weisser P . Separation of a hyaluronate-free lubricating fraction from synovial fluid. Nature. 1970; 228(5269):377-8. DOI: 10.1038/228377a0. View

Decker B, McGUCKIN W, McKENZIE B, Slocumb C . Concentration of hyaluronic acid in synovial fluid. Clin Chem. 1959; 5:465-9. View

Hodge W, Carlson K, Fijan R, Burgess R, Riley P, Harris W . Contact pressures from an instrumented hip endoprosthesis. J Bone Joint Surg Am. 1989; 71(9):1378-86. View

Crockett R, Grubelnik A, Roos S, Dora C, Born W, Troxler H . Biochemical composition of the superficial layer of articular cartilage. J Biomed Mater Res A. 2007; 82(4):958-64. DOI: 10.1002/jbm.a.31248. View

Bao J, Chen W, Wu L . Lubricin: a novel potential biotherapeutic approaches for the treatment of osteoarthritis. Mol Biol Rep. 2010; 38(5):2879-85. DOI: 10.1007/s11033-010-9949-9. View

WRIGHT V, Dowson D . Lubrication and cartilage. J Anat. 1976; 121(Pt 1):107-18. PMC: 1231823. View

Hills B, Monds M . Enzymatic identification of the load-bearing boundary lubricant in the joint. Br J Rheumatol. 1998; 37(2):137-42. DOI: 10.1093/oxfordjournals.rheumatology.a031463. View

10.

Walker P, Dowson D, Longfield M, WRIGHT V . "Boosted lubrication" in synovial joints by fluid entrapment and enrichment. Ann Rheum Dis. 1968; 27(6):512-20. PMC: 1010471. DOI: 10.1136/ard.27.6.512. View

11.

Chan S, Neu C, DuRaine G, Komvopoulos K, Reddi A . Atomic force microscope investigation of the boundary-lubricant layer in articular cartilage. Osteoarthritis Cartilage. 2010; 18(7):956-63. DOI: 10.1016/j.joca.2010.03.012. View

12.

Jay G, Cha C . The effect of phospholipase digestion upon the boundary lubricating ability of synovial fluid. J Rheumatol. 1999; 26(11):2454-7. View

13.

Swann D, Slayter H, Silver F . The molecular structure of lubricating glycoprotein-I, the boundary lubricant for articular cartilage. J Biol Chem. 1981; 256(11):5921-5. View

14.

Morlock M, Schneider E, Bluhm A, Vollmer M, Bergmann G, Muller V . Duration and frequency of every day activities in total hip patients. J Biomech. 2001; 34(7):873-81. DOI: 10.1016/s0021-9290(01)00035-5. View

15.

Ateshian G . The role of interstitial fluid pressurization in articular cartilage lubrication. J Biomech. 2009; 42(9):1163-76. PMC: 2758165. DOI: 10.1016/j.jbiomech.2009.04.040. View

16.

Pawlak Z, Oloyede A . Conceptualisation of articular cartilage as a giant reverse micelle: a hypothetical mechanism for joint biocushioning and lubrication. Biosystems. 2008; 94(3):193-201. DOI: 10.1016/j.biosystems.2008.05.028. View

17.

McNary S, Athanasiou K, Reddi A . Engineering lubrication in articular cartilage. Tissue Eng Part B Rev. 2011; 18(2):88-100. PMC: 3311401. DOI: 10.1089/ten.TEB.2011.0394. View

18.

Sarma A, Powell G, LaBerge M . Phospholipid composition of articular cartilage boundary lubricant. J Orthop Res. 2001; 19(4):671-6. DOI: 10.1016/S0736-0266(00)00064-4. View

19.

Hills B . Oligolamellar nature of the articular surface. J Rheumatol. 1990; 17(3):349-56. View

20.

Wong M, Carter D . Articular cartilage functional histomorphology and mechanobiology: a research perspective. Bone. 2003; 33(1):1-13. DOI: 10.1016/s8756-3282(03)00083-8. View