Optical Characterization of Oligonucleotide DNA Influenced by Magnetic Fields

Overview

Journal Molecules

Publisher MDPI

Specialty Biology

Date 2013 Sep 28

PMID 24071986

Citations 5

Authors

Seyedeh Maryam Banihashemian

Vengadesh Periasamy

Seyed Mohammad Hossein Mousa Kazemi Mohammadi

Richard Ritikos

Saadah Abdul Rahman

Affiliations

Soon will be listed here.

Abstract

UV-VIS spectroscopic analysis of oligonucleotide DNA exposed to different magnetic fields was performed in order to investigate the relationship between DNA extinction coefficients and optical parameters according to magnetic-field strength. The results with the oligonucleotides adenine-thymine 100 mer (AT-100 DNA) and cytosine-guanine 100 mer (CG-100 DNA) indicate that the magnetic field influences DNA molar extinction coefficients and refractive indexes. The imaginary parts of the refractive index and molar extinction coefficients of the AT-100 and CG-100 DNA decreased after exposure to a magnetic field of 750 mT due to cleavage of the DNA oligonucleotides into smaller segments.

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References

Cantor C, WARSHAW M, Shapiro H . Oligonucleotide interactions. 3. Circular dichroism studies of the conformation of deoxyoligonucleotides. Biopolymers. 1970; 9(9):1059-77. DOI: 10.1002/bip.1970.360090909. View

Houssier C, Kuball H . Electro-optical properties of nucleic acids and nucleoproteins. 3. Kramers-Kronig relationships in linear birefringence and dichroism. Application to a DNA-proflavine complex. Biopolymers. 1971; 10(12):2421-33. DOI: 10.1002/bip.360101206. View

Magbanua E, Zivkovic T, Hansen B, Beschorner N, Meyer C, Lorenzen I . d(GGGT) 4 and r(GGGU) 4 are both HIV-1 inhibitors and interleukin-6 receptor aptamers. RNA Biol. 2012; 10(2):216-27. PMC: 3594281. DOI: 10.4161/rna.22951. View

De Vlaminck I, Henighan T, van Loenhout M, Burnham D, Dekker C . Magnetic forces and DNA mechanics in multiplexed magnetic tweezers. PLoS One. 2012; 7(8):e41432. PMC: 3411724. DOI: 10.1371/journal.pone.0041432. View

Dhar S, Daniel W, Giljohann D, Mirkin C, Lippard S . Polyvalent oligonucleotide gold nanoparticle conjugates as delivery vehicles for platinum(IV) warheads. J Am Chem Soc. 2009; 131(41):14652-3. PMC: 2761975. DOI: 10.1021/ja9071282. View

Thompson D, Enright A, Faulds K, Smith W, Graham D . Ultrasensitive DNA detection using oligonucleotide-silver nanoparticle conjugates. Anal Chem. 2008; 80(8):2805-10. DOI: 10.1021/ac702403w. View

Foy S, Manthe R, Foy S, Dimitrijevic S, Krishnamurthy N, Labhasetwar V . Optical imaging and magnetic field targeting of magnetic nanoparticles in tumors. ACS Nano. 2010; 4(9):5217-24. PMC: 2947615. DOI: 10.1021/nn101427t. View

Chakeres D, De Vocht F . Static magnetic field effects on human subjects related to magnetic resonance imaging systems. Prog Biophys Mol Biol. 2004; 87(2-3):255-65. DOI: 10.1016/j.pbiomolbio.2004.08.012. View

Cavaluzzi M, Borer P . Revised UV extinction coefficients for nucleoside-5'-monophosphates and unpaired DNA and RNA. Nucleic Acids Res. 2004; 32(1):e13. PMC: 373314. DOI: 10.1093/nar/gnh015. View

10.

Lan G, Chen W, Chang H . One-pot synthesis of fluorescent oligonucleotide Ag nanoclusters for specific and sensitive detection of DNA. Biosens Bioelectron. 2010; 26(5):2431-5. DOI: 10.1016/j.bios.2010.10.026. View

11.

Tempestini A, Cassina V, Brogioli D, Ziano R, Erba S, Giovannoni R . Magnetic tweezers measurements of the nanomechanical stability of DNA against denaturation at various conditions of pH and ionic strength. Nucleic Acids Res. 2012; 41(3):2009-19. PMC: 3561983. DOI: 10.1093/nar/gks1206. View

12.

Mahmoudi Khatir N, Banihashemian S, Periasamy V, Ritikos R, Majid W, Rahman S . Electrical characterization of gold-DNA-gold structures in presence of an external magnetic field by means of I-V curve analysis. Sensors (Basel). 2012; 12(3):3578-3586. PMC: 3376582. DOI: 10.3390/s120303578. View

13.

Chen H, Fu H, Zhu X, Cong P, Nakamura F, Yan J . Improved high-force magnetic tweezers for stretching and refolding of proteins and short DNA. Biophys J. 2011; 100(2):517-23. PMC: 3325116. DOI: 10.1016/j.bpj.2010.12.3700. View

14.

Ichioka S, Iwasaka M, Shibata M, Harii K, Kamiya A, Ueno S . Biological effects of static magnetic fields on the microcirculatory blood flow in vivo: a preliminary report. Med Biol Eng Comput. 1998; 36(1):91-5. DOI: 10.1007/BF02522863. View