» Articles » PMID: 24063537

Headache and Comorbidity in Children and Adolescents

Abstract

Headache is one of the most common neurological symptom reported in childhood and adolescence, leading to high levels of school absences and being associated with several comorbid conditions, particularly in neurological, psychiatric and cardiovascular systems. Neurological and psychiatric disorders, that are associated with migraine, are mainly depression, anxiety disorders, epilepsy and sleep disorders, ADHD and Tourette syndrome. It also has been shown an association with atopic disease and cardiovascular disease, especially ischemic stroke and patent foramen ovale (PFO).

Citing Articles

Efficacy of prophylactic sodium valproate in pediatric migraines: a systematic review of randomized clinical studies.

Askar G, Askar O, Altuhafy M, Nagi R, Khan J Transl Pediatr. 2025; 13(12):2254-2266.

PMID: 39823012 PMC: 11732630. DOI: 10.21037/tp-24-279.


Headaches and adolescents: why so many failures in their management.

Cucchiaro G, Frye W Eur J Pediatr. 2024; 184(1):61.

PMID: 39627547 PMC: 11614951. DOI: 10.1007/s00431-024-05834-7.


The Photo- and Phonosensitivity Avoidance Behavior Scales: Evaluating Clinical Utility in Pediatric Primary Chronic Headache.

Smith A, Silvia M, Rogan H, Lebel A Children (Basel). 2024; 11(11).

PMID: 39594913 PMC: 11593221. DOI: 10.3390/children11111338.


A multi-centre, tolerability study of a cannabidiol-enriched Cannabis Herbal Extract for chronic headaches in adolescents: The CAN-CHA protocol.

Chhabra M, Lewis E, Balshaw R, Stewart B, Zaslawski Z, Lowthian T PLoS One. 2024; 19(9):e0290185.

PMID: 39302982 PMC: 11414974. DOI: 10.1371/journal.pone.0290185.


Migraine and Epilepsy in Children: A Narrative Review of Comorbidity and Similar Treatment Option.

Momen A, Jelodar G, Azizimalamiri R Iran J Child Neurol. 2024; 18(3):9-20.

PMID: 38988846 PMC: 11231672. DOI: 10.22037/ijcn.v18i3.44282.


References
1.
Lipton R, Silberstein S . Why study the comorbidity of migraine?. Neurology. 1994; 44(10 Suppl 7):S4-5. View

2.
Mitsikostas D, Thomas A . Comorbidity of headache and depressive disorders. Cephalalgia. 1999; 19(4):211-7. DOI: 10.1046/j.1468-2982.1999.019004211.x. View

3.
DE ROMANIS F, Buzzi M, Cerbo R, Feliciani M, Assenza S, Agnoli A . Migraine and epilepsy with infantile onset and electroencephalographic findings of occipital spike-wave complexes. Headache. 1991; 31(6):378-83. DOI: 10.1111/j.1526-4610.1991.hed3106378.x. View

4.
Breslau J, Miller E, Breslau N, Bohnert K, Lucia V, Schweitzer J . The impact of early behavior disturbances on academic achievement in high school. Pediatrics. 2009; 123(6):1472-6. PMC: 2778327. DOI: 10.1542/peds.2008-1406. View

5.
De Simone R, Ranieri A, Marano E, Beneduce L, Ripa P, Bilo L . Migraine and epilepsy: clinical and pathophysiological relations. Neurol Sci. 2007; 28 Suppl 2:S150-5. DOI: 10.1007/s10072-007-0769-1. View