Prevalence, Aetiology and Antibiotic Resistance Profiles of Coagulase Negative Staphylococci Isolated in a Teaching Hospital

Overview

Journal Braz J Microbiol

Specialty Microbiology

Date 2013 Sep 14

PMID 24031628

Citations 7

Authors

Luiz S Keim

Sylvio R Torres-Filho

Patricia Vollu Silva

Lenise A Teixeira

Affiliations

Soon will be listed here.

Abstract

In this paper we carried out a study about prevalence of the clinically significant coagulase negative staphylococcal (CNS) isolates found in an university hospital. Two hundred four CNS isolates from 191 patients obtained between the period of 1998 to 2002, were studied. About 27% (52/191) of the infection cases studied were confirmed as CNS-associated diseases. Blood stream infection (BSI) was the most frequent CNS associated-disease (25%; 13/52). The great majority of the BSI was verified in the Neonatal Intensive Care Unit (NICU). The analysis of the 52 patients medical history showed that 85% of the BSI was acquired in hospital. Most of the CNS nosocomial infections were associated with the use of indwelling medical devices. The incidence of methicillin-resistance among significant CNS isolates was 38%. In this study, a high percentage of exogenous contaminant was verified (60%), indicating that contamination of clinical specimens during sample collection is critical.

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