Endoscopic Removal of Symptomatic Gastric Heterotopic Pancreas: a Report of Nine Cases

Aims: The aim of this study was to evaluate the efficacy and safety of endoscopic removal of symptomatic gastric heterotopic pancreas (HP).

Patients And Methods: From January 2010 to December 2011, 9 patients with suspected symptomatic HP were enrolled in the study. Endoscopic ultrasonography was performed to clarify the HP tissue location and to choose the endoscopic resection method. Endoscopic mucosal resection or endoscopic submucosal dissection was performed to remove the HP tissue. Symptoms in the enrolled patients were assessed before and after endoscopic removal of the HP tissue. Tumor pathology and complications were recorded after the treatment. A standard follow-up was scheduled at 1 week and 2 months after treatment.

Results: Removal of suspected HP with endoscopic mucosal resection or endoscopic submucosal dissection was successful in all 9 cases. Abdominal pain, leukocytosis, and bleeding occurred in 6 patients, 2 patients, and 1 patient, respectively, after treatment and were relieved by symptomatic treatment. There were no other unpredictable complications. The symptoms related to HP, including epigastric pain, bloating, and postprandial fullness, were relieved significantly after the treatment. During follow-up, there was no recurrence of HP in any patient.

Conclusions: Endoscopic removal appears to be a safe and effective method to treat gastric lesions suspected to be HP with symptoms. The symptoms, such as epigastric pain, bloating, and postprandial fullness were well resolved after endoscopic treatment.