Assessing HIV and AIDS Treatment Safety and Health-related Quality of Life Among Cohort of Malaysian Patients: a Discussion on Methodological Approach

Overview

Journal Health Expect

Publisher Wiley

Specialty Public Health

Date 2013 Sep 10

PMID 24010818

Citations 1

Authors

Imran Ahmed Syed

Syed Azhar Syed Sulaiman

Mohammad Azmi Hassali

Christopher K C Lee

Affiliations

Soon will be listed here.

Abstract

Background: Health-related quality of life (HRQoL) is increasingly recognized as an important outcome and as a complement to traditional biological end points of diseases such as mortality. Unless there is a complete cure available for HIV/AIDS, development and implementation of a reliable and valid cross cultural quality of life measure is necessary to assess not only the physical and medical needs of HIV/AIDS people, but their psychological, social, environmental, and spiritual areas of life.

Methods: A qualitative exploration of HIV/AIDS patients' understanding, perceptions and expectations will be carried out with the help of semi structured interview guide by in depth interviews, while quantitative assessment of patient reported adverse drug reactions and their impact on health related quality of life will be carried out by using data collection tool comprising patient demographics, SF-12, Naranjo scale, and a clinical data sheet.

Results/outcomes: The findings may serve as baseline QOL data of people living with HIV/AIDS in Malaysia and also a source data to aid construction of management plan to improve HIV/AIDS patients' QOL. It will also provide basic information about HIV/AIDS patients' perceptions, expectations and believes towards HIV/AIDS and its treatment which may help in designing strategies to enhance patients' awareness which in turn can help in addressing issues related to compliance and adherence.

Citing Articles

Gender disparity in health-related quality of life among people living with HIV/AIDS in Ethiopia: a systematic review and meta-analysis.

Tufa D, Tola H, Dissassa H, Geleta L, Malka E, Tadesse A Front Glob Womens Health. 2024; 5:1471316.

PMID: 39635356 PMC: 11614810. DOI: 10.3389/fgwh.2024.1471316.

References

Gold R, Ridge D . "I will start treatment when I think the time is right": HIV-positive gay men talk about their decision not to access antiretroviral therapy. AIDS Care. 2001; 13(6):693-708. DOI: 10.1080/09540120120076869. View

Chandra P, Satyanarayana V, Satishchandra P, Satish K, Kumar M . Do men and women with HIV differ in their quality of life? A study from South India. AIDS Behav. 2008; 13(1):110-7. PMC: 2886199. DOI: 10.1007/s10461-008-9434-9. View

Gold R, Hinchy J, Batrouney C . The reasoning behind decisions not to take up antiretroviral therapy in Australians infected with HIV. Int J STD AIDS. 2000; 11(6):361-70. DOI: 10.1258/0956462001916065. View

Pereira M, Canavarro M . Gender and age differences in quality of life and the impact of psychopathological symptoms among HIV-infected patients. AIDS Behav. 2011; 15(8):1857-69. DOI: 10.1007/s10461-011-9928-8. View

Misener T, Sowell R . HIV-infected women's decisions to take antiretrovirals. West J Nurs Res. 1998; 20(4):431-47. DOI: 10.1177/019394599802000403. View

Horne R, Cooper V, Gellaitry G, Date H, Fisher M . Patients' perceptions of highly active antiretroviral therapy in relation to treatment uptake and adherence: the utility of the necessity-concerns framework. J Acquir Immune Defic Syndr. 2007; 45(3):334-41. DOI: 10.1097/QAI.0b013e31806910e3. View

Siegel K, Gorey E . HIV-infected women: barriers to AZT use. Soc Sci Med. 1997; 45(1):15-22. DOI: 10.1016/s0277-9536(96)00303-6. View

Preau M, Leport C, Salmon-Ceron D, Carrieri P, Portier H, Chene G . Health-related quality of life and patient-provider relationships in HIV-infected patients during the first three years after starting PI-containing antiretroviral treatment. AIDS Care. 2004; 16(5):649-61. DOI: 10.1080/09540120410001716441. View

Murri R, Guaraldi G, Lupoli P, Crisafulli R, Marcotullio S, von Schloesser F . Rate and predictors of self-chosen drug discontinuations in highly active antiretroviral therapy-treated HIV-positive individuals. AIDS Patient Care STDS. 2009; 23(1):35-9. DOI: 10.1089/apc.2007.0248. View

10.

Wisniewski A, Apel S, Selnes O, Nath A, McArthur J, Dobs A . Depressive symptoms, quality of life, and neuropsychological performance in HIV/AIDS: the impact of gender and injection drug use. J Neurovirol. 2005; 11(2):138-43. DOI: 10.1080/13550280590922748. View

11.

Collins E, Wagner C, Walmsley S . Psychosocial impact of the lipodystrophy syndrome in HIV infection. AIDS Read. 2000; 10(9):546-50. View

12.

Cooper V, BUICK D, Horne R, Lambert N, Gellaitry G, Leake H . Perceptions of HAART among gay men who declined a treatment offer: preliminary results from an interview-based study. AIDS Care. 2002; 14(3):319-28. DOI: 10.1080/09540120220123694. View

13.

Almeida R, Vieira A . Evaluation of HIV/AIDS patients' knowledge on antiretroviral drugs. Braz J Infect Dis. 2010; 13(3):183-90. DOI: 10.1590/s1413-86702009000300006. View

14.

Tramarin A, Parise N, Campostrini S, Yin D, Postma M, Lyu R . Association between diarrhea and quality of life in HIV-infected patients receiving highly active antiretroviral therapy. Qual Life Res. 2004; 13(1):243-50. DOI: 10.1023/B:QURE.0000015282.24774.36. View

15.

Pitt J, Myer L, Wood R . Quality of life and the impact of drug toxicities in a South African community-based antiretroviral programme. J Int AIDS Soc. 2009; 12:5. PMC: 2683808. DOI: 10.1186/1758-2652-12-5. View

16.

Farooqui M, Hassali M, Shatar A, Shafie A, Seang T, Farooqui M . A qualitative exploration of Malaysian cancer patients' perspectives on cancer and its treatment. BMC Public Health. 2011; 11:525. PMC: 3146868. DOI: 10.1186/1471-2458-11-525. View

17.

Siegel K, Raveis V, Krauss B . Factors associated with urban gay men's treatment initiation decisions for HIV infection. AIDS Educ Prev. 1992; 4(2):135-42. View

18.

Mrus J, Williams P, Tsevat J, Cohn S, Wu A . Gender differences in health-related quality of life in patients with HIV/AIDS. Qual Life Res. 2005; 14(2):479-91. DOI: 10.1007/s11136-004-4693-z. View

19.

Nicholas P, Kirksey K, Corless I, Kemppainen J . Lipodystrophy and quality of life in HIV: symptom management issues. Appl Nurs Res. 2005; 18(1):55-8. DOI: 10.1016/j.apnr.2004.09.012. View

20.

Liu C, Weber K, Robison E, Hu Z, Jacobson L, Gange S . Assessing the effect of HAART on change in quality of life among HIV-infected women. AIDS Res Ther. 2006; 3:6. PMC: 1459186. DOI: 10.1186/1742-6405-3-6. View