Control of Vertebrate Development by MYC

Overview

Journal Cold Spring Harb Perspect Med

Specialty General Medicine

Date 2013 Sep 5

PMID 24003246

Citations 27

Authors

Peter J Hurlin

Affiliations

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Abstract

The study of MYC has led to pivotal discoveries in cancer biology, induced pluripotency, and transcriptional regulation. In this review, continuing advances in our understanding of the function of MYC as a transcription factor and how its transcriptional activity controls normal vertebrate development and contributes to developmental disorders is discussed.

Citing Articles

Untangling the Role of MYC in Sarcomas and Its Potential as a Promising Therapeutic Target.

Sias F, Zoroddu S, Migheli R, Bagella L Int J Mol Sci. 2025; 26(5).

PMID: 40076599 PMC: 11900228. DOI: 10.3390/ijms26051973.

Exploring the dynamics and interactions of the N-myc transactivation domain through solution nuclear magnetic resonance spectroscopy.

Rejnowicz E, Batchelor M, Leen E, Ahangar M, Burgess S, Richards M Biochem J. 2024; 481(21):1535-1556.

PMID: 39370942 PMC: 11555651. DOI: 10.1042/BCJ20240248.

MYC function and regulation in physiological perspective.

Jha R, Kouzine F, Levens D Front Cell Dev Biol. 2023; 11:1268275.

PMID: 37941901 PMC: 10627926. DOI: 10.3389/fcell.2023.1268275.

Mitochondrial Factors in the Cell Nucleus.

Gonzalez-Arzola K, Diaz-Quintana A Int J Mol Sci. 2023; 24(17).

PMID: 37686461 PMC: 10563088. DOI: 10.3390/ijms241713656.

Alterations and Co-Occurrence of C-MYC, N-MYC, and L-MYC Expression are Related to Clinical Outcomes in Various Cancers.

Lee M, Seok J, Saha S, Cho S, Jeong Y, Gil M Int J Stem Cells. 2023; 16(2):215-233.

PMID: 37105559 PMC: 10226856. DOI: 10.15283/ijsc22188.

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