Amide I Band and Photoinduced Disassembly of a Peptide Hydrogel

Overview

Journal Chem Phys Lett

Date 2013 Sep 3

PMID 23997272

Citations 3

Authors

Thomas J Measey

Beatrice N Markiewicz

Feng Gai

Affiliations

Soon will be listed here.

Abstract

Peptide hydrogels are promising candidates for a wide range of medical and biotechnological applications. To further expand the potential utility of peptide hydrogels, herein we demonstrate a simple yet effective strategy to render peptide hydrogels photodegradable, making controlled disassembly of the gel structure of interest feasible. In addition, we find that the high-frequency amide I' component (i.e., the peak at ~1685 cm) of the photodegradable peptide hydrogel studied shows an unusually large enhancement, in comparison to that of other peptide fibrils consisting of antiparallel β-sheets, making it a good model system for further study of the coupling-structure relationship.

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