Understanding of Latent Tuberculosis, Its Treatment and Treatment Side Effects in Immigrant and Refugee Patients

Overview

Journal BMC Res Notes

Publisher Biomed Central

Specialties Biology
General Medicine

Date 2013 Aug 31

PMID 23987744

Citations 7

Authors

Katie Butcher

Beverley-Ann Biggs

Karin Leder

Chris Lemoh

Daniel OBrien

Caroline Marshall

Affiliations

Soon will be listed here.

Abstract

Background: Isoniazid treatment of latent tuberculosis infection (LTBI) is commonly prescribed in refugees and immigrants. We aimed to assess understanding of information provided about LTBI, its treatment and potential side effects.

Methods: A questionnaire was administered in clinics at a tertiary hospital. Total Knowledge (TKS) and Total Side Effect Scores (TSES) were derived. Logistic regression analyses were employed to correlate socio-demographic factors with knowledge.

Results: Fifty-two participants were recruited, 20 at isoniazid commencement and 32 already on isoniazid. The average TKS were 5.04/9 and 6.23/9 respectively and were significantly associated with interpreter use. Approximately half did not know how tuberculosis was transmitted. The average TSES were 5.0/7 and 3.5/7 respectively, but were not influenced by socio-demographic factors.

Conclusions: There was suboptimal knowledge about LTBI. Improvements in health messages delivered via interpreters and additional methods of distributing information need to be developed for this patient population.

Citing Articles

Barriers and facilitators of tuberculosis treatment among immigrants: an integrative review.

Seyedmehdi S, Jamaati H, Varahram M, Tabarsi P, Marjani M, Moniri A BMC Public Health. 2024; 24(1):3514.

PMID: 39696110 PMC: 11658328. DOI: 10.1186/s12889-024-21020-8.

How can we improve latent tuberculosis infection management using behaviour change wheel: a systematic review.

Wong Y, Ng K, Lee S J Public Health (Oxf). 2023; 45(3):e447-e466.

PMID: 37147919 PMC: 10470485. DOI: 10.1093/pubmed/fdad051.

Novel Assay Platform to Evaluate Intracellular Killing of : and Validation.

Horvati K, Fodor K, Palyi B, Henczko J, Balka G, Gyulai G Front Immunol. 2021; 12:750496.

PMID: 34867981 PMC: 8632718. DOI: 10.3389/fimmu.2021.750496.

Protocol for a cluster randomised control trial evaluating the efficacy and safety of treatment for latent tuberculosis infection in recent migrants within primary care: the CATAPuLT trial.

Burman M, Copas A, Zenner D, Hickson V, Gosce L, Trathen D BMC Public Health. 2019; 19(1):1598.

PMID: 31783742 PMC: 6884916. DOI: 10.1186/s12889-019-7983-7.

Detailed characterisation of the tuberculosis epidemic in Western Sydney: a descriptive epidemiological study.

Norton S, Bag S, Cho J, Heron N, Assareh H, Pavaresh L ERJ Open Res. 2019; 5(3).

PMID: 31528636 PMC: 6734008. DOI: 10.1183/23120541.00211-2018.

References

Coreil J, Lauzardo M, Heurtelou M . Cultural feasibility assessment of tuberculosis prevention among persons of Haitian origin in South Florida. J Immigr Health. 2004; 6(2):63-9. DOI: 10.1023/B:JOIH.0000019166.80968.70. View

Ailinger R, Armstrong R, Nguyen N, Lasus H . Latino immigrants' knowledge of tuberculosis. Public Health Nurs. 2004; 21(6):519-23. DOI: 10.1111/j.0737-1209.2004.21603.x. View

Page K, Sifakis F, Montes de Oca R, Cronin W, Doherty M, Federline L . Improved adherence and less toxicity with rifampin vs isoniazid for treatment of latent tuberculosis: a retrospective study. Arch Intern Med. 2006; 166(17):1863-70. DOI: 10.1001/archinte.166.17.1863. View

Houston H, Harada N, Makinodan T . Development of a culturally sensitive educational intervention program to reduce the high incidence of tuberculosis among foreign-born Vietnamese. Ethn Health. 2003; 7(4):255-65. DOI: 10.1080/1355785022000060718. View

Hirsch-Moverman Y, Daftary A, Franks J, Colson P . Adherence to treatment for latent tuberculosis infection: systematic review of studies in the US and Canada. Int J Tuberc Lung Dis. 2008; 12(11):1235-54. View

Matteelli A, Casalini C, Raviglione M, El-Hamad I, Scolari C, Bombana E . Supervised preventive therapy for latent tuberculosis infection in illegal immigrants in Italy. Am J Respir Crit Care Med. 2000; 162(5):1653-5. DOI: 10.1164/ajrccm.162.5.9912062. View

Cain K, Haley C, Armstrong L, Garman K, Wells C, Iademarco M . Tuberculosis among foreign-born persons in the United States: achieving tuberculosis elimination. Am J Respir Crit Care Med. 2006; 175(1):75-9. DOI: 10.1164/rccm.200608-1178OC. View

Marks G, Bai J, Simpson S, Sullivan E, Stewart G . Incidence of tuberculosis among a cohort of tuberculin-positive refugees in Australia: reappraising the estimates of risk. Am J Respir Crit Care Med. 2000; 162(5):1851-4. DOI: 10.1164/ajrccm.162.5.2004154. View

. Targeted tuberculin testing and treatment of latent tuberculosis infection. This official statement of the American Thoracic Society was adopted by the ATS Board of Directors, July 1999. This is a Joint Statement of the American Thoracic Society.... Am J Respir Crit Care Med. 2000; 161(4 Pt 2):S221-47. DOI: 10.1164/ajrccm.161.supplement_3.ats600. View

10.

Ito K . Health culture and the clinical encounter: Vietnamese refugees' responses to preventive drug treatment of inactive tuberculosis. Med Anthropol Q. 1999; 13(3):338-64. DOI: 10.1525/maq.1999.13.3.338. View

11.

Gibney K, MacGregor L, Leder K, Torresi J, Marshall C, Ebeling P . Vitamin D deficiency is associated with tuberculosis and latent tuberculosis infection in immigrants from sub-Saharan Africa. Clin Infect Dis. 2008; 46(3):443-6. DOI: 10.1086/525268. View

12.

Shieh F, Snyder G, Horsburgh C, Bernardo J, Murphy C, Saukkonen J . Predicting non-completion of treatment for latent tuberculous infection: a prospective survey. Am J Respir Crit Care Med. 2006; 174(6):717-21. DOI: 10.1164/rccm.200510-1667OC. View

13.

Wyss L, Alderman M . Using theory to interpret beliefs in migrants diagnosed with latent TB. Online J Issues Nurs. 2007; 12(1):7. View

14.

. Trends in tuberculosis--United States, 2008. MMWR Morb Mortal Wkly Rep. 2009; 58(10):249-53. View

15.

Hess K, Goad J, Wu J, Johnson K . Isoniazid completion rates for latent tuberculosis infection among college students managed by a community pharmacist. J Am Coll Health. 2009; 57(5):553-5. DOI: 10.3200/JACH.57.5.553-556. View

16.

Maartens G, Wilkinson R . Tuberculosis. Lancet. 2007; 370(9604):2030-43. DOI: 10.1016/S0140-6736(07)61262-8. View

17.

Menzies D, Long R, Trajman A, Dion M, Yang J, Al Jahdali H . Adverse events with 4 months of rifampin therapy or 9 months of isoniazid therapy for latent tuberculosis infection: a randomized trial. Ann Intern Med. 2008; 149(10):689-97. DOI: 10.7326/0003-4819-149-10-200811180-00003. View

18.

Gibney K, Mihrshahi S, Torresi J, Marshall C, Leder K, Biggs B . The profile of health problems in African immigrants attending an infectious disease unit in Melbourne, Australia. Am J Trop Med Hyg. 2009; 80(5):805-11. View

19.

Ailinger R, Moore J, Nguyen N, Lasus H . Adherence to latent tuberculosis infection therapy among latino immigrants. Public Health Nurs. 2006; 23(4):307-13. DOI: 10.1111/j.1525-1446.2006.00566.x. View

20.

Lopez-Velez R, Huerga H, Turrientes M . Infectious diseases in immigrants from the perspective of a tropical medicine referral unit. Am J Trop Med Hyg. 2003; 69(1):115-21. View