The Synthesis of Biologically Relevant Conjugates of Re(CO) Using Pyridine-2-carboxyaldehyde

Overview

Journal J Organomet Chem

Specialty Chemistry

Date 2013 Aug 27

PMID 23976791

Citations 4

Authors

Roshinee Costa

Kullapa Chanawanno

James T Engle

Bertha Baroody

Richard S Herrick

Christopher J Ziegler

Affiliations

Soon will be listed here.

Abstract

The new pyridine-2-carboxaldehyde adduct, Re(CO)(NCHC(O)H)Cl and previously reported complex Re(CO)(NCHC(O)H)Br react with aniline derivatives sulfanilamide or 4-aminofluorescein in methanol giving Schiff base conjugates Re(CO)(pyca-R)X (pyca = pyridinecarbaldehyde imine, X = Cl, Br), -. Pre-isolation of compounds and provides a convenient method for preparing conjugate complexes in addition to the known methods of ligand synthesis and one-pot reactions. All new compounds were completely characterized, and compound and the sulfanilamide derivatives and were structurally elucidated by X-ray crystallography.

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