Five-year Clinical Performance of a HEMA-free One-step Self-etch Adhesive in Noncarious Cervical Lesions

Overview

Journal Clin Oral Investig

Specialty Dentistry

Date 2013 Aug 17

PMID 23949016

Citations 6

Authors

Kirsten L van Landuyt

Jan de Munck

R Banu Ermis

Marleen Peumans

Bart Van Meerbeek

Affiliations

Soon will be listed here.

Abstract

Objectives: The objective of this randomized controlled trial was to evaluate the clinical performance of a 2-hydroxyethyl methacrylate (HEMA)-free one-step adhesive.

Materials And Methods: Two hundred sixty-seven cervical lesions in 52 patients were restored with the composite Gradia Direct (GC), bonded with either the one-step self-etch adhesive G-Bond (GC) or the three-step etch-and-rinse adhesive Optibond FL (Kerr) in a random order. The restorations were evaluated for retention, marginal integrity, marginal discoloration, and caries occurrence after 5 years. Specific statistics were used to account for the clustered data (multiple restorations per patient).

Results: The clinical success rate for G-Bond (87.4 %) was not significantly different from that of Optibond FL (90.9 %). Both adhesives showed progressive marginal deterioration, but G-Bond exhibited more small enamel defects and marginal discoloration, and unlike previous recalls, several restorations failed because of deep microleakage. Large sclerotic lesions were a significant risk factor for retention loss with G-Bond. Irrespective of the adhesive, almost all restorations with retention loss were located in the lower jaw.

Conclusion: After 5 years of clinical service, restorations bonded with the HEMA-free one-step adhesive did not need repair or replacement more often than those with the three-step etch-and-rinse adhesive, and both adhesives had a high retention rate (>90 %). There were indications that G-Bond did not (self-)etch enough in some clinical situations, as G-Bond exhibited more incisal defects and marginal discolorations, and sclerotic lesions were at higher risk of retention loss.

Clinical Relevance: The clinical performance of the HEMA-free one-step adhesive was clinically acceptable after 5 years.

Citing Articles

HEMA-free versus HEMA-containing adhesive systems: a systematic review.

Abdelkhalek E, Hamama H, Mahmoud S Syst Rev. 2025; 14(1):17.

PMID: 39838443 PMC: 11748282. DOI: 10.1186/s13643-025-02763-w.

Effect of the Adhesive Strategy on Clinical Performance and Marginal Integrity of a Universal Adhesive in Non-Carious Cervical Lesions in a Randomized 36-Month Study.

Haak R, Stache G, Schneider H, Hafer M, Schmalz G, Schulz-Kornas E J Clin Med. 2023; 12(18).

PMID: 37762718 PMC: 10531668. DOI: 10.3390/jcm12185776.

Fourteen-year Clinical Performance of a HEMA-free One-step Self-etch Adhesive in Non-carious Cervical Lesions.

Peumans M, Van de Maele E, de Munck J, van Landuyt K, Van Meerbeek B J Adhes Dent. 2023; 25():147-158.

PMID: 37435814 PMC: 11734294. DOI: 10.3290/j.jad.b4208859.

Three-year Clinical Performance of a Universal Adhesive in Non-Carious Cervical Lesions.

Peumans M, Vandormael S, De Coster I, de Munck J, Van Meerbeek B J Adhes Dent. 2023; 25():133-146.

PMID: 37387551 PMC: 11734268. DOI: 10.3290/j.jad.b4186751.

Clinical Outcomes and Quantitative Margin Analysis of a Universal Adhesive Using a Randomized Clinical Trial over Three Years.

Haak R, Werner M, Schneider H, Hafer M, Schulz-Kornas E J Clin Med. 2022; 11(23).

PMID: 36498485 PMC: 9737201. DOI: 10.3390/jcm11236910.

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