Mapping the Human Gene Coding for Chromosomal Protein HMG-17

Overview

Journal Hum Genet

Specialty Genetics

Date 1990 Aug 1

PMID 2394451

Citations 5

Authors

N Popescu

D Landsman

M Bustin

Affiliations

Soon will be listed here.

Abstract

The functional gene coding for nonhistone chromosomal protein HMG-17, a nucleosomal binding protein that may confer unique properties to the chromatin structure of active genes, has been mapped to band 1p36.1. The multiple, nonfunctional, HMG-17 retropseudogenes are scattered over several chromosomes.

Citing Articles

Increased expression of high-mobility group nucleosomal-binding domain 2 protein in various tumor cell lines.

Li Q, Chen J, Li X, Cui B, Fan Y, Geng N Oncol Lett. 2018; 15(4):4517-4522.

PMID: 29541221 PMC: 5835874. DOI: 10.3892/ol.2018.7898.

Evolution of high mobility group nucleosome-binding proteins and its implications for vertebrate chromatin specialization.

Gonzalez-Romero R, Eirin-Lopez J, Ausio J Mol Biol Evol. 2014; 32(1):121-31.

PMID: 25281808 PMC: 4271525. DOI: 10.1093/molbev/msu280.

HMGN2, a new anti-tumor effector molecule of CD8⁺ T cells.

Su L, Hu A, Luo Y, Zhou W, Zhang P, Feng Y Mol Cancer. 2014; 13:178.

PMID: 25060707 PMC: 4126642. DOI: 10.1186/1476-4598-13-178.

Nucleosome-binding protein HMGN2 exhibits antitumor activity in oral squamous cell carcinoma.

Hu A, Dong X, Liu X, Zhang P, Zhang Y, Su N Oncol Lett. 2013; 7(1):115-120.

PMID: 24348831 PMC: 3861564. DOI: 10.3892/ol.2013.1665.

Identification and genetic mapping of the murine gene and 20 related sequences encoding chromosomal protein HMG-17.

Johnson K, Cook S, Bustin M, Davisson M Mamm Genome. 1993; 4(2):83-9.

PMID: 8094303 DOI: 10.1007/BF00290431.

References

PASH J, Popescu N, Matocha M, Rapoport S, Bustin M . Chromosomal protein HMG-14 gene maps to the Down syndrome region of human chromosome 21 and is overexpressed in mouse trisomy 16. Proc Natl Acad Sci U S A. 1990; 87(10):3836-40. PMC: 53998. DOI: 10.1073/pnas.87.10.3836. View

Weisbrod S . Active chromatin. Nature. 1982; 297(5864):289-95. DOI: 10.1038/297289a0. View

Einck L, Bustin M . The intracellular distribution and function of the high mobility group chromosomal proteins. Exp Cell Res. 1985; 156(2):295-310. DOI: 10.1016/0014-4827(85)90539-7. View

Srikantha T, Landsman D, Bustin M . Retropseudogenes for human chromosomal protein HMG-17. J Mol Biol. 1987; 197(3):405-13. DOI: 10.1016/0022-2836(87)90554-7. View

Tronick S, Popescu N, Cheah M, Swan D, Amsbaugh S, Lengel C . Isolation and chromosomal localization of the human fgr protooncogene, a distinct member of the tyrosine kinase gene family. Proc Natl Acad Sci U S A. 1985; 82(19):6595-9. PMC: 391256. DOI: 10.1073/pnas.82.19.6595. View

Popescu N, Amsbaugh S, Swan D, DIPAOLO J . Induction of chromosome banding by trypsin/EDTA for gene mapping by in situ hybridization. Cytogenet Cell Genet. 1985; 39(1):73-4. DOI: 10.1159/000132107. View

Petersen M, Economou E, Slaugenhaupt S, Chakravarti A, Antonarakis S . Linkage analysis of the human HMG14 gene on chromosome 21 using a GT dinucleotide repeat as polymorphic marker. Genomics. 1990; 7(1):136-8. DOI: 10.1016/0888-7543(90)90531-x. View

Popescu N, Amsbaugh S, DIPAOLO J, Tronick S, Aaronson S, Swan D . Chromosomal localization of three human ras genes by in situ molecular hybridization. Somat Cell Mol Genet. 1985; 11(2):149-55. DOI: 10.1007/BF01534703. View

Weintraub H, Groudine M . Chromosomal subunits in active genes have an altered conformation. Science. 1976; 193(4256):848-56. DOI: 10.1126/science.948749. View

10.

Dracopoli N, Stanger B, Lager M, Housman D . Localization of the FGR protooncogene on the genetic linkage map of human chromosome 1p. Genomics. 1988; 3(2):124-8. DOI: 10.1016/0888-7543(88)90142-5. View

11.

Landsman D, Soares N, Gonzalez F, Bustin M . Chromosomal protein HMG-17. Complete human cDNA sequence and evidence for a multigene family. J Biol Chem. 1986; 261(16):7479-84. View

12.

Landsman D, MCBRIDE O, Bustin M . Human non-histone chromosomal protein HMG-17: identification, characterization, chromosome localization and RFLPs of a functional gene from the large multigene family. Nucleic Acids Res. 1989; 17(6):2301-14. PMC: 317597. DOI: 10.1093/nar/17.6.2301. View