Surgical Treatment Options and Management Strategies of Metastatic Renal Cell Carcinoma to the Lumbar Spinal Nerve Roots

Overview

Journal J Clin Neurosci

Specialty Neurology

Date 2013 Aug 13

PMID 23931936

Citations 12

Authors

Christian Strong

Vijay Yanamadala

Arjun Khanna

Brian P Walcott

Brian V Nahed

Lawrence F Borges

Jean-Valery C E Coumans

Affiliations

Soon will be listed here.

Abstract

Spinal nerve root metastasis of renal cell carcinoma is a rare occurrence. In addition to treatment of the primary lesion, surgical resection of the nerve root metastasis, occasionally with sacrifice of the involved nerve, is the accepted standard of treatment. Resection often resolves presenting motor and pain symptoms due to relief of neural compression. We describe two patients with nerve root metastasis of renal cell carcinoma and their management. While locally advanced and metastatic renal cell carcinoma has been shown to be chemo- and radio-resistant, immunotherapy is a promising treatment. Given the high prevalence of systemic disease in patients with intradural metastases, systemic (and possibly intracranial) imaging can be used to identify other potential areas of disease.

Citing Articles

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Multiple nerve root metastasis of breast carcinoma: a report of two cases.

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Intradural extramedullary spinal metastasis of renal cell carcinoma: illustrative case report and comprehensive review of the literature.

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