PH-Switchable Ampholytic Supramolecular Copolymers

Overview

Journal Angew Chem Int Ed Engl

Specialty Chemistry

Date 2013 Aug 10

PMID 23929814

Citations 25

Authors

Hendrik Frisch

Jan Patrick Unsleber

David Ludeker

Martin Peterlechner

Gunther Brunklaus

Mark Waller

Pol Besenius

Affiliations

Soon will be listed here.

Abstract

β-sheet-encoded anionic and cationic dendritic peptide amphiphiles form supramolecular copolymers when self-assembled in a 1:1 feed ratio of the monomers. These ampholytic materials have been designed for on-off polymerization in response to pH triggers. The cooperative supramolecular self-assembly process is switched on at a physiologically relevant pH value and can be switched off by increasing or decreasing the pH value.

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