Plasmodium Falciparum Malaria: Proteomic Studies

Overview

Journal Rev Bras Ter Intensiva

Specialties Critical Care
General Medicine

Date 2013 Aug 7

PMID 23917939

Citations 2

Authors

Rodrigo Siqueira-Batista

Andreia Patricia Gomes

Eduardo Gomes de Mendonca

Rodrigo Roger Vitorino

Sarah Fumian Milward de Azevedo

Rodrigo de Barros Freitas

Luiz Alberto Santana

Maria Goreti de Almeida Oliveira

Affiliations

Soon will be listed here.

Abstract

Despite advances in treatment and campaigns for prevention and control of malaria on the various continents where it is still rampant, this disease remains significantly relevant to the contemporary world. Plasmodium falciparum is the organism that is mainly responsible for severe malaria, which is characterized by disturbances in different organs and systems, with possibly fatal outcomes. Although incipient, proteomic studies of malaria have yielded favorable prospects for elucidating the biological aspects of Plasmodium as well as the pathophysiological, diagnostic, prophylactic, and therapeutic mechanisms of the disease. Thus, the aim of the present article is to present a brief review of the applications of proteomic analysis in P. falciparum malaria.

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