Animal Models of Axon Regeneration After Spinal Cord Injury

Overview

Journal Neurosci Bull

Specialty Neurology

Date 2013 Jul 30

PMID 23893429

Citations 27

Authors

Do-Hun Lee

Jae K Lee

Affiliations

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Abstract

With advances in genetic and imaging techniques, investigating axon regeneration after spinal cord injury in vivo is becoming more common in the literature. However, there are many issues to consider when using animal models of axon regeneration, including species, strains and injury models. No single particular model suits all types of experiments and each hypothesis being tested requires careful selection of the appropriate animal model. in this review, we describe several commonly-used animal models of axon regeneration in the spinal cord and discuss their advantages and disadvantages.

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