A Pilot Study of Training and Compensation Interventions for Mild Cognitive Impairment

Overview

Journal Dement Geriatr Cogn Dis Extra

Publisher Karger

Specialty Geriatrics

Date 2013 Jul 27

PMID 23888165

Citations 4

Authors

Susanna Konsztowicz

Jerine Anton

Joelle Crane

Parastoo Moafmashhadi

Lisa Koski

Affiliations

Soon will be listed here.

Abstract

Background: This pilot clinical trial sought to estimate the feasibility and efficacy of two interventions aimed at improving memory performance in geriatric clinic patients with mild cognitive impairment.

Methods: Fifteen participants were randomized to either a memory training group or a memory compensation group.

Results: Recruitment rates were low, whereas adherence and retention rates were acceptable. The memory training group improved in self-reported memory abilities and satisfaction with memory. The memory compensation group improved on one objective memory test but showed no consistent changes on any other outcomes.

Conclusion: Effect size estimates will inform the design of larger clinical trials.

Citing Articles

Evaluating the Real-World Representativeness of Participants with Mild Cognitive Impairment in Canadian Research Protocols: a Comparison of the Characteristics of a Memory Clinic Patients and Research Samples.

Huang V, Hogan D, Ismail Z, Maxwell C, Smith E, Callahan B Can Geriatr J. 2020; 23(4):297-328.

PMID: 33282050 PMC: 7704078. DOI: 10.5770/cgj.23.416.

Differential effects of cognitive training modules in healthy aging and mild cognitive impairment: A comprehensive meta-analysis of randomized controlled trials.

Basak C, Qin S, OConnell M Psychol Aging. 2020; 35(2):220-249.

PMID: 32011155 PMC: 7050567. DOI: 10.1037/pag0000442.

Everyday Impact of Cognitive Interventions in Mild Cognitive Impairment: a Systematic Review and Meta-Analysis.

Chandler M, Parks A, Marsiske M, Rotblatt L, Smith G Neuropsychol Rev. 2016; 26(3):225-251.

PMID: 27632385 PMC: 5048589. DOI: 10.1007/s11065-016-9330-4.

Attempted and successful compensation in preclinical and early manifest neurodegeneration - a review of task FMRI studies.

Scheller E, Minkova L, Leitner M, Kloppel S Front Psychiatry. 2014; 5:132.

PMID: 25324786 PMC: 4179340. DOI: 10.3389/fpsyt.2014.00132.

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